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Triglycerides is a term used to refer to the circulating levels of fatty acids (similar in structure to dietary fatty acids, and fat mass) that can be measured via a blood test. Although crucial for energy usage, excessively high circulating Triglycerides is a risk factor for circulatory problems.

Research analysis lead by Kamal Patel
All content reviewed by Examine.com Team. Published:
Last Updated:

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect triglycerides
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
grade-a Fish Oil Strong Very High See all 44 studies
Fish oil, both EPA and DHA, are reference drugs for the purpose of reducing triglycerides with highly reliable reductions in the range of 15-30% (higher reductions seen in persons with higher baseline triglycerides)
grade-a Garlic Minor Very High See all 15 studies
There appears to be quite an unreliable decrease in triglycerides following garlic supplementation. When looking at meta-analyses, there is either a significant but small decrease or a reduction that fails to reach statistical significance.
grade-a Chromium - Very High See all 17 studies
Chromium does not appear to have a role in reducing triglyceride concentrations in the serum of subjects, including diabetic subjects given chromium supplementation.
grade-a Cocoa Extract  
grade-a Red Clover Extract  
grade-b Spirulina  
grade-b Vitamin B3 (Niacin)  
grade-b Berberine  
grade-b Conjugated Linoleic Acid  
grade-b Curcumin  
grade-b Inositol  
grade-b Nigella sativa  
grade-b Astaxanthin  
grade-b Dehydroepiandrosterone  
grade-b Grape Seed Extract  
grade-b Hesperidin  
grade-b L-Carnitine  
grade-b Lactobacillus reuteri  
grade-b Magnesium  
grade-b Olive leaf extract  
grade-b Policosanol  
grade-b Psyllium  
grade-b Vitamin C  
grade-b Vitamin E  
grade-c Hibiscus sabdariffa  
grade-c Tetradecyl Thioacetic Acid  
grade-c Ashwagandha  
grade-c Cissus quadrangularis  
grade-c Citrullus colocynthis  
grade-c Ephedrine  
grade-c Fenugreek  
grade-c Fucoxanthin  
grade-c Ganoderma lucidum  
grade-c Ginger  
grade-c Irvingia gabonensis  
grade-c Krill Oil  
grade-c Melatonin  
grade-c Punicic Acid  
grade-c Resveratrol  
grade-c Rooibos  
grade-c Shilajit  
grade-c Vanadium  
grade-c Vitamin D  
grade-c Whey Protein  
grade-c Anethum graveolens  
grade-c Artichoke Extract  
grade-c Benfotiamine  
grade-c Biotin  
grade-c Black Cohosh  
grade-c Blueberry  
grade-c Caffeine  
grade-c Creatine  
grade-c Ecdysteroids  
grade-c Ecklonia cava  
grade-c Eleutherococcus senticosus  
grade-c Gamma Oryzanol  
grade-c Garcinia cambogia  
grade-c Green Coffee Extract  
grade-c Green Tea Catechins  
grade-c Guggul  
grade-c Gynostemma pentaphyllum  
grade-c Hemp Protein  
grade-c Japanese Knotweed  
grade-c Lactobacillus casei  
grade-c Licorice  
grade-c Microlactin  
grade-c Nattokinase  
grade-c Panax ginseng  
grade-c Phosphatidylcholine  
grade-c Phosphatidylserine  
grade-c Pterostilbene  
grade-c Rose Hip  
grade-c Royal Jelly  
grade-c Salvia hispanica  
grade-c Sea Buckthorn  
grade-c Soy lecithin  
grade-c Stevia  
grade-c Theaflavins  
grade-c Trimethylglycine  
grade-c Vitamin K  
grade-c Yacon  
grade-c Zinc  
grade-d Aronia melanocarpa  
grade-d Colostrum  
grade-d Eclipta alba  
grade-d Emblica officinalis  
grade-d HMB  
grade-d Mangifera indica  
grade-d Medium-chain triglycerides  
grade-d Perilla Oil  
grade-d Pycnogenol  
grade-d Pyrroloquinoline quinone  
grade-d Rubus coreanus  
grade-d Ruscus aculeatus  
grade-d Safflower Oil  
grade-d Tribulus terrestris  
grade-d Vitamin B1  

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.