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Green Coffee Extract

Green Coffee Extract is a concentrated source of dietary Chlorogenic Acid and is currently being used for heart health and fat loss as a supplement; it seems weakly to moderately effective on these parameters.

Our evidence-based analysis on green coffee extract features 18 unique references to scientific papers.

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Summary of Green Coffee Extract

Primary information, health benefits, side effects, usage, and other important details

Green Coffee extract is a supplement and/or food product that is derived from Green Coffee Beans. For all intents and purposes, it has similar chemical composition to coffee beans in general but has a much higher content of molecules known as Chlorogenic Acid; a term used to refer to molecules that have small phenolics bound to a Quinic acid group.

The Chlorogenic Acids in Green Coffee Extract are readily absorbed, and they themselves or their metabolites (such as ferulic acid) mediate many of the benefits of Green Coffee Extract. Supplementing Chlorogenic Acid should also, theoretically, confer much of the same benefits as Green Coffee Extract (and vice versa).

Oral ingestion of Green Coffee Extract may weakly reduce body weight in overweight and obese persons (mechanisms currently unknown, thought to be related to preventing carbohydrate uptake from the intestines after a meal) although the degree of weight reduction seems quite unreliable at this moment in time; studies in lean persons are nonexistent right now. A handful of studies suggest that 'blood health' can be improved via increase vasoreactivity and lowered blood pressure, which have been shown to benefit people with poor vascular function or high blood pressure; this may only be a bandaid effect (with one study noting that 2 weeks after cessation the beneficial changes were being normalized) and may be due to the ferulic acid metabolite.

Green Coffee Extract is indeed healthy, but for the benefits it is touted for it does not appear to be as potent as some other supplements.

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How to Take

Medical Disclaimer

Recommended dosage, active amounts, other details

Studies using Green Coffee Extract (GCE) tend to be dosed based on their chlorogenic acid content, which in isolation are taken in the 120-300mg range. Based on this, recommended intakes of GCE would be approximately:

  • 1,200-3,000mg for a 10% chlorogenic acid supplement

  • 600-1,500mg for a 20% chlorogenic acid supplement

  • 240-600mg for a 50% chlorogenic acid supplement

The optimal dosage of both GCE and isolated chlorogenic acid is not known at this moment in time.

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Human Effect Matrix

Unlocked for Examine members

The Human Effect Matrix summarizes human studies to tell you what effects Green Coffee Extract has on your body, how much evidence there is, and how strong these effects are.

Full details are available to Examine members.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-c Notable - See study
Decrease in blood pressure noted with green coffee extract ingestion, due to the chlorogenic acid component. Degree of reduction reached 10mmHg (from just above 145mmHg to just above 135mmHg) and is quite notable.
grade-c Minor - See study
Lone study to measure fat mass noted a decrease associated with green coffee extract consumption, but this is similarly confounded with industrial influence.
grade-c Minor - See study
A decrease has been noted in hypertensives alongside a reduction in blood pressure; no studies in otherwise healthy persons
grade-c Minor - See study
Decrease in homocysteine noted, thought to be indicative of cardioprotection
grade-c Minor - See study
An increase in vascular responsiveness has been noted with green coffee extract, thought to be due to the metabolite ferulic acid
grade-c Minor Moderate See 2 studies
There may be a weight reducing effect, but currently the literature is too influenced by industrial producers of GCE and the magnitude of effect seems too large. Independent replication is needed.
grade-c - - See study
No significant influence noted on fasting glucose levels (may reduce postprandial slightly)
grade-c - - See study
No alterations noted in creatinine associated with green coffee extract intake
grade-c - - See study
No significant alterations in HDL cholesterol noted following consumption of GCE
grade-c - - See study
LDL cholesterol appears unaffected
grade-c - - See study
No significant influence noted for liver enzymes when tested in part of a safety assay
grade-c - - See study
No significant alterations in total cholesterol seen with green coffee extract
grade-c - - See study
No significant influence on triglycerides following oral intake
grade-c - - See study
No significant alterations in WBC count

Studies Excluded from Consideration

  • The Meta-Analysis[1] (conclusions drawn from research with a high risk of bias; excluded as to avoid an undeserving A rating in the above table)

  • Removed[2] due to being retracted[3]

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Things to Note

Other Functions:

Primary Function:

Do Not Confuse With

Chlorogenic Acid (Main ingredient)

  • If it possible to be allergic to Green Coffee Extracts, which should be related to an allergy to coffee beans and extracts in general

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Click here to see all 18 references.