Benfotiamine
•Last Updated: November 17 2022
Benfotiamine is a relative of the vitamin Thiamine (B1) that appears to have a therapeutic role in pain reduction and diabetic complications (neuropathies and nephropathies); confers bioavailable Vitamin B1 after oral ingestion.
Benfotiamine is most often used for
Last Updated: November 17 2022
Note that Benfotiamine is also known as:
- S-{(Z)-2-{(4-amino-2-methylpyrimidin-5-yl) methyl-formylamino}-5-phosphonooxypent-2-en-3-yl} benzenecarbothioate
Benfotiamine should not be confused with:
- Sulbutiamine (a molecule made from two Thiamin molecules; very different actions though)
Benfotiamine is commonly taken at the oral dose of 300-600mg over the course of the day, usually in two divided doses with meals (150mg or 300mg twice daily).
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47.^High prevalence of low plasma thiamine concentration in diabetes linked to a marker of vascular disease.()
48.^Beltramo E, Nizheradze K, Berrone E, Tarallo S, Porta MThiamine and benfotiamine prevent apoptosis induced by high glucose-conditioned extracellular matrix in human retinal pericytesDiabetes Metab Res Rev.(2009 Oct)
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