Tetradecyl Thioacetic Acid

Last Updated: September 28 2022

Technically an Omega-3 fatty acid, TTA is a non-metabolizable fatty acid that cannot be used for energy and may be able to burn fat via mechanisms similar to Conjugated Linoleic Acid. Lacking studies in humans at the moment, TTA appears to be a promising future candidate for fat loss and health.

Tetradecyl Thioacetic Acid is most often used for


Tetradecyl Thioacetic Acid, otherwise known as TTA, is what is known as a PPAR-alpha activator. It is actually an omega-3 fatty acid, but has a sulfur group at the omega-3 position; because of this addition it cannot be burnt for energy and thus has no relevant caloric value to humans.

PPARa activation can be seen as protecting the body from excess fats (similar to PPARy activation). PPARa tends to clear fats from the blood into muscle or liver cells, and encourage them to be burnt for energy in these locations (by comparison, PPARy makes new fat cells for fats to reside in which minimizes their potential toxicity).

The clearing of fat from the blood causes a drop in lipoproteins and a lowering of LDL cholesterol, and the burning of fats causes either fat burning or reduced fat gain. TTA can also decrease blood pressure and exert an anti-oxidant effect, the four mechanisms making it a cardioprotective compound.

It is commonly used with the appetite suppressant oleoylethanolamide as a fat-burning combination.

What else is Tetradecyl Thioacetic Acid known as?
Note that Tetradecyl Thioacetic Acid is also known as:
  • TTA
Dosage information

Not much evidence currently exists in human, but the standard dose appears to be 1g of TTA daily taken in divided dosages with meals.

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