Psoriasis is a chronic skin disease that causes patches of thick, red, scaly skin on various parts of the body. Its cause is unknown and symptoms tend to wax and wane over time.
Psoriasis is a chronic inflammatory skin disease where skin cells regenerate too quickly and form thick, red patches of skin with white or silver scales. A 2017 study found that up to 11% of adults and 1.4% of children worldwide have psoriasis.
Psoriasis typically looks like elevated lesions that are red, dry, and have silvery scales. They can appear anywhere on the body, such as:
The diagnosis is largely clinical, based on the appearance of the rash and associated symptoms. A healthcare professional must first rule out other diseases that may cause similar symptoms. During a visit with a healthcare professional, a clinical history is acquired and a comprehensive skin evaluation is done.
Treatment is determined by the extent and severity of symptoms. Medical treatments include:
- Topical creams (e.g. steroids and moisturizers)
- Oral or injected medications (e.g. immunosuppressants)
- Phototherapy (exposing skin to different wavelengths of light)
Topical treatments are used for milder cases. If there is no response to topical treatments or for more severe cases, immunosuppressants and/or phototherapy (a treatment that uses ultraviolet light) may be used.
Dietary supplements are often sought out to relieve symptoms of psoriasis. Supplements with the most evidence include:
Some studies show that the above supplements are either beneficial or ineffective. More rigorous research is needed before recommendations can be made.
Observational studies have demonstrated that people with psoriasis consume a lower amount of foods typically found in a Mediterranean diet (e.g., olive oil, fruits, fish, nuts, and whole grains). Research using dietary interventions found that a hypocaloric diet in overweight or obese people with psoriasis or a gluten-free diet in people with a gluten sensitivity shows the most promise for helping reduce symptoms of psoriasis. It is recommended that changes in diet should be used alongside standard medical treatments.
Psoriasis is thought to be caused by an excessive immune response, which results in an overabundance of skin cells regenerating. The development of psoriasis includes a combination of genetic, environmental, and psychological components.
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- ^The content of this page was partially adapted from MedlinePlus of the National Library of Medicine
- ^I M Michalek, B Loring, S M JohnA systematic review of worldwide epidemiology of psoriasisJ Eur Acad Dermatol Venereol.(2017 Feb)
- ^April W Armstrong, Charlotte ReadPathophysiology, Clinical Presentation, and Treatment of Psoriasis: A ReviewJAMA.(2020 May 19)
- ^Naoko Kanda, Toshihiko Hoashi, Hidehisa SaekiNutrition and PsoriasisInt J Mol Sci.(2020 Jul 29)
- ^Céline Phan, Mathilde Touvier, Emmanuelle Kesse-Guyot, Moufidath Adjibade, Serge Hercberg, Pierre Wolkenstein, Olivier Chosidow, Khaled Ezzedine, Emilie SbidianAssociation Between Mediterranean Anti-inflammatory Dietary Profile and Severity of Psoriasis: Results From the NutriNet-Santé CohortJAMA Dermatol.(2018 Sep 1)
- ^Luigi Barrea, Nicola Balato, Carolina Di Somma, Paolo Emidio Macchia, Maddalena Napolitano, Maria Cristina Savanelli, Katherine Esposito, Annamaria Colao, Silvia SavastanoNutrition and psoriasis: is there any association between the severity of the disease and adherence to the Mediterranean diet?J Transl Med.(2015 Jan 27)
- ^Adam R Ford, Michael Siegel, Jerry Bagel, Kelly M Cordoro, Amit Garg, Alice Gottlieb, Lawrence J Green, Johann E Gudjonsson, John Koo, Mark Lebwohl, Wilson Liao, Arthur M Mandelin 2nd, Joseph A Markenson, Nehal Mehta, Joseph F Merola, Ronald Prussick, Caitriona Ryan, Sergio Schwartzman, Evan L Siegel, Abby S Van Voorhees, Jashin J Wu, April W ArmstrongDietary Recommendations for Adults With Psoriasis or Psoriatic Arthritis From the Medical Board of the National Psoriasis Foundation: A Systematic ReviewJAMA Dermatol.(2018 Aug 1)
- ^Frank Peinemann, Marco Harari, Sandra Peternel, Thalia Chan, David Chan, Alexander M Labeit, Thilo GambichlerIndoor salt water baths followed by artificial ultraviolet B light for chronic plaque psoriasisCochrane Database Syst Rev.(2020 May 5)
- ^A Caresse Gamret, Alexandra Price, Raymond M Fertig, Hadar Lev-Tov, Anna J NicholsComplementary and Alternative Medicine Therapies for Psoriasis: A Systematic ReviewJAMA Dermatol.(2018 Nov 1)
- ^David Boothe W, Tarbox JA, Tarbox MBAtopic Dermatitis: Pathophysiology.Adv Exp Med Biol.(2017)
- ^Reynolds KA, Pithadia DJ, Lee EB, Liao W, Wu JJA systematic review of treatment strategies for erythrodermic psoriasis.J Dermatolog Treat.(2021-Feb)
- ^Ritchlin CT, Colbert RA, Gladman DDPsoriatic Arthritis.N Engl J Med.(2017-03-09)
- Psoriasis Symptoms - Allan SJ, Kavanagh GM, Herd RM, Savin JAThe effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trialBr J Dermatol.(2004 May)
- Psoriasis Symptoms - Padilla HC, Laínez H, Pacheco JAA new agent (hydrophilic fraction of polypodium leucotomos) for management of psoriasisInt J Dermatol.(1974 Sep-Oct)
- Psoriasis Symptoms - Sadeghian G, Ziaei H, Nilforoushzadeh MATreatment of localized psoriasis with a topical formulation of zinc pyrithioneActa Dermatovenerol Alp Panonica Adriat.(2011)
- Total cholesterol - Morken T, Bohov P, Skorve J, Ulvik R, Aukrust P, Berge RK, Livden JKAnti-inflammatory and hypolipidemic effects of the modified fatty acid tetradecylthioacetic acid in psoriasis--a pilot studyScand J Clin Lab Invest.(2011 Jul)