Boron

Last Updated: September 28 2022

Boron is a dietary mineral which is claimed to increase testosterone when supplemented at doses higher than from food, but research is lacking. It might as a byproduct of its anti-inflammatory effects.

Boron is most often used for

What is boron?

Boron is a trace mineral with biological effects, though its essentiality is debated.

What are boron's benefits?

It seems to be able to reduce levels of inflammatory markers, and may reduce rheumatoid arthritis, osteoarthritis, and menstural cramps, though much more research is needed before we can be confident in these benefits. It also might have a small positive effect on LDL-cholesterol, but this is far from certain.

What are boron's side-effects and drawbacks?

It seems to be generally safe, though human research on its adverse effects is lacking, so smaller doses may be warranted.

Dosage information

The lowest active dose of Boron supplementation appears to be 3mg, which is effective in supporting hormonal parameters in postmenopausal women. Studies on osteoarthritis have used 6mg of Boron while studies in youth investigating hormonal changes have used 10mg.

The optimal dose is currently not known, but the above doses appear to be active for their aforementioned goals.

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References
1.^Hunt CD, Shuler TR, Mullen LMConcentration of boron and other elements in human foods and personal-care productsJ Am Diet Assoc.(1991 May)
2.^Siegel E, Wason SBoric acid toxicityPediatr Clin North Am.(1986 Apr)
4.^Loomis WD, Durst RWChemistry and biology of boronBiofactors.(1992 Apr)
5.^Devirian TA1, Volpe SLThe physiological effects of dietary boronCrit Rev Food Sci Nutr.(2003)
12.^Liao SF1, Monegue JS, Lindemann MD, Cromwell GL, Matthews JCDietary supplementation of boron differentially alters expression of borate transporter (NaBCl) mRNA by jejunum and kidney of growing pigsBiol Trace Elem Res.(2011 Nov)
13.^Damkier HH1, Nielsen S, Praetorius JMolecular expression of SLC4-derived Na+-dependent anion transporters in selected human tissuesAm J Physiol Regul Integr Comp Physiol.(2007 Nov)
14.^Wallace JM, Hannon-Fletcher MP, Robson PJ, Gilmore WS, Hubbard SA, Strain JJBoron supplementation and activated factor VII in healthy menEur J Clin Nutr.(2002 Nov)
15.^Naghii MR, Mofid M, Asgari AR, Hedayati M, Daneshpour MSComparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokinesJ Trace Elem Med Biol.(2011 Jan)
16.^Samman S1, Naghii MR, Lyons Wall PM, Verus APThe nutritional and metabolic effects of boron in humans and animalsBiol Trace Elem Res.(1998 Winter)
20.^Penland JGDietary boron, brain function, and cognitive performanceEnviron Health Perspect.(1994 Nov)
22.^Naghii MR, Samman SThe role of boron in nutrition and metabolismProg Food Nutr Sci.(1993 Oct-Dec)
23.^Newnham REEssentiality of boron for healthy bones and jointsEnviron Health Perspect.(1994 Nov)
29.^Lee IP, Sherins RJ, Dixon RLEvidence for induction of germinal aplasia in male rats by environmental exposure to boronToxicol Appl Pharmacol.(1978 Aug)
30.^Gonzalez A, Peters U, Lampe JW, White EBoron intake and prostate cancer riskCancer Causes Control.(2007 Dec)
31.^Barranco WT, Hudak PF, Eckhert CDEvaluation of ecological and in vitro effects of boron on prostate cancer risk (United States)Cancer Causes Control.(2007 Feb)
32.^Naghii MR, Einollahi B, Rostami ZPreliminary evidence hints at a protective role for boron in urolithiasisJ Altern Complement Med.(2012 Mar)
36.^Duydu Y, Başaran N, Üstündağ A, Aydin S, Ündeğer Ü, Ataman OY, Aydos K, Düker Y, Ickstadt K, Waltrup BS, Golka K, Bolt HMReproductive toxicity parameters and biological monitoring in occupationally and environmentally boron-exposed persons in Bandirma, TurkeyArch Toxicol.(2011 Jun)
37.^Pizent A, Tariba B, Živković TReproductive toxicity of metals in menArh Hig Rada Toksikol.(2012)
38.^Korkmaz M, Yenigün M, Bakırdere S, Ataman OY, Keskin S, Müezzinoğlu T, Lekili MEffects of chronic boron exposure on semen profileBiol Trace Elem Res.(2011 Nov)
39.^Robbins WA, Xun L, Jia J, Kennedy N, Elashoff DA, Ping LChronic boron exposure and human semen parametersReprod Toxicol.(2010 Apr)
40.^Weir RJ Jr, Fisher RSToxicologic studies on borax and boric acidToxicol Appl Pharmacol.(1972 Nov)