Quick Navigation

Boron

Boron is a dietary mineral which is claimed to increase testosterone when supplemented at doses higher than from food, but research is lacking. It might as a byproduct of its anti-inflammatory effects.

Our evidence-based analysis on boron features 47 unique references to scientific papers.

Research analysis led by .
Reviewed by
Examine.com Team
Last Updated:

Summary of Boron

Primary information, health benefits, side effects, usage, and other important details

What is boron?

Boron is a trace mineral with biological effects, though its essentiality is debated.

What are boron's benefitS?

It seems to be able to reduce levels of inflammatory markers, and may reduce rheumatoid arthritis, osteoarthritis, and menstural cramps, though much more research is needed before we can be confident in these benefits. It also might have a small positive effect on LDL-cholesterol, but this is far from certain.

What are boron's side-effects and drawbacks?

It seems to be generally safe, though human research on its adverse effects is lacking, so smaller doses may be warranted.

Make sure you only take supplements that work

Examine.com bases all of its recommendations on published scientific research. We’re a trusted resource because we don’t sell or even advertise supplements.

If you’re tired of wasting time and money on supplements that don’t work, our 17 Supplement Guides will help you figure out precisely what to take — and what to skip — based on your health goals and the latest scientific evidence. There’s a reason why over 50,000 customers rely on Examine.com’s independent and unbiased analysis.

Includes free lifetime updates so you always have the most accurate information.


I want unbiased recommendations to improve my health »

How to Take

Medical Disclaimer

Recommended dosage, active amounts, other details

The lowest active dose of Boron supplementation appears to be 3mg, which is effective in supporting hormonal parameters in postmenopausal women. Studies on osteoarthritis have used 6mg of Boron while studies in youth investigating hormonal changes have used 10mg.

The optimal dose is currently not known, but the above doses appear to be active for their aforementioned goals.

Get the latest information on 400+ supplements and their effects on 600+ health conditions & outcomes.

By becoming an Examine Plus member, you'll have access to all of the latest nutrition research. Quickly and easily look up scientific research on over 400 supplements across over 600 different health goals, outcomes, conditions, and more.

Already a subscriber to any of our membership plans? Click here to login.

Human Effect Matrix

Unlocked for Examine Plus members

The Human Effect Matrix summarizes human studies to tell you what effects Boron has on your body, how much evidence there is, and how strong these effects are.

Full details are available to Examine Plus members.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-c Notable Very High See all 5 studies
Most studies found notable reductions, with calcium fructoborate being the most supported form.
grade-d Notable - See study
One study in young women found a meaningful improvement in pain and duration of menstrual cramps.
grade-d Notable Very High See 2 studies
There was a notable reduction with low, medium, or high doses in people with osteoarthritis. and rheumatoid arthritis.
grade-d Notable - See study
There was a notable reduction in one study in healthy participants, with no notable difference between 1.5 mg and 3 mg of calcium fructoborate.
grade-d Notable Very High See 2 studies
Notable reductions have been found in people with rheumatoid arthritis and healthy participants.
grade-d Notable - See study
There was a notable reduction in one study, when taken on its own or combined with resveratrol compared with control and resveratrol alone.
grade-d Notable - See study
One study in young women found a modest improvement in pain and duration of menstrual cramps. No other symptoms of PMS have been evaluated.
grade-d Notable - See study
There was a notable reduction in knee pain in one study on people with knee discomfort.
grade-d Notable - See study
There was a notable reduction in overall symptoms in a study on people with knee discomfort but who hasn't necessarily been diagnosed with osteoarthritis of the knee.
grade-d Notable - See study
There was a notable reduction from sodium tetraborate and calcium fructoborate in one small study. Calcium fructoborate looked somewhat more potent.
grade-d Notable - See study
There was a notable reduction in one study on people with rheumatoid arthritis. Calcium fructoborate was more effective than sodium tetraborate.
grade-d
Minor
Low See all 3 studies
Appears to influence estrogen, seems unreliable in its mechanisms and is likely context dependent. Both increases and decreases have been noted
grade-d Minor - See study
There was somewhat of a reduction in people with osteoarthritis in one study.
grade-d Minor Very High See 2 studies
Appears to be somewhat effective, but requires some more robust trials
grade-d Minor - See study
There was a small decrease in healthy participants in one study.
grade-d Minor - See study
Some influence on typically inflammatory cytokines, practical relevance of these changes unknown
grade-d Minor - See study
Calcium fructoborate led to a notable reduction in one study in participants with rheumatoid arthritis, while calcium tetraborate only led to a small reduction.
grade-d Minor - See study
Appears effective, but no comparison to a reference drug nor control group thus far
grade-d Minor High See all 3 studies
Somewhat of a reduction in participants with high LDL has been noted in 3 studies.
grade-d
Minor
- See study
One crossover study found a small increase in alkaline phosphatase when boron was taken second, but not when taken first. More research is needed to verify this.
grade-d Minor - See study
A small reduction was noted in one study. More studies are needed to verify this.
grade-d Minor - See study
There was a reduction in one study on healthy participants. 3 mg of boron from calcium fructoborate was modestly more effective than 1.5 mg.
grade-d Minor - See study
There was somewhat of an increase in one study from 3 mg of chelates of citrate, aspartate, and glycinate.
grade-d
Minor
- See study
There was both an increase and a decrease in a crossover trial when boron was taken first or second.
grade-d
Minor
- See study
There was both a small increase and a decrease in a crossover study depending on whether boron was taken first or second.
grade-d Minor High See all 3 studies
There appears to be somewhat of an interaction with boron and testosterone in both genders, but it is seemingly unreliable
grade-d
Minor
- See study
While not statistically significant, boron saw a small increase when taken first in a crossover trial, but not when taken second.
grade-d Minor Very High See all 3 studies
Studies have generally found a small reduction in people with elevated levels.
grade-d Minor - See study
There was somewhat of an increase in one study of peri-menopausal women. More research is needed to verify this.
grade-d - - See study
There was no effect in participants with healthy blood sugar levels in one study.
grade-d - - See study
No apparent effect in one study of normal weight males.
grade-d - - See study
No significant effect on cortisol has been noted with supplemental boron
grade-d - - See study
No significant influences on serum DHT noted
grade-d - - See study
There was an increase in one crossover study when it was taken second, but not when it was taken first.
grade-d - High See all 3 studies
Studies don't suggest a meaningful effect overall.
grade-d - - See study
No apparent effect in one study.
grade-d - - See study
No apparent effect in one study from 3 mg of chelates of citrate, aspartate, and glycinate.
grade-d - - See study
No apparent effect on 1-rep max squats and benchpress in men involved in a training program.
grade-d - High See all 3 studies
The studies don't consistently suggest a meaningful effect

Become an Examine Plus member to access the latest nutrition research on over 400 supplements across over 600 different health goals, outcomes, conditions, and more.

Becoming an Examine Plus member not only unlocks the Human Effect Matrix for supplements, but also all health topics on Examine.com. We neatly summarize all the latest research so you can make the best decisions for your health based on what's accurate and not out-dated information.

Click here to see all 47 references.