Boron
The lowest active dose of Boron supplementation appears to be 3mg, which is effective in supporting hormonal parameters in postmenopausal women. Studies on osteoarthritis have used 6mg of Boron while studies in youth investigating hormonal changes have used 10mg.
The optimal dose is currently not known, but the above doses appear to be active for their aforementioned goals.
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Human Effect Matrix
The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what effects boron has on your body, and how strong these effects are.
| Grade | Level of Evidence [show legend] |
|---|---|
|
Robust research conducted with repeated double-blind clinical trials |
|
Multiple studies where at least two are double-blind and placebo controlled |
|
Single double-blind study or multiple cohort studies |
|
Uncontrolled or observational studies only |
|
Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
|
Outcome |
Magnitude of effect
?
The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
|
Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
|
Notes |
|---|---|---|---|---|
|
|
 
Minor
|
- See 2 studies |
Appears to influence estrogen, seems unreliable in its mechanisms and is likely context dependent. Both increases and decreases have been noted
|
|
|
|
Minor
|
- See study |
Appears to be quite effective, but requires some more robust trials
|
|
|
|
Minor
|
- See study |
Some influence on typically inflammatory cytokines, practical relevance of these changes unknown
|
|
|
|
Minor
|
- See study |
Appears effective, but no comparison to a reference drug nor control group thus far
|
|
|
|
Minor
|
Moderate See 2 studies |
There appears to be an interaction with Boron and testosterone in both genders, but it is seemingly unreliable
|
|
|
|
- | - See study |
No significant effect on this inflammatory biomarker
|
|
|
|
- | - See study |
No significant effect on cortisol has been noted with supplemental boron
|
|
|
|
- | - See study |
No significant influences on serum DHT noted
|
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