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Symptoms of Rheumatoid Arthritis

Rheumatoid arthritis is an autoimmune form of arthritis that is associated with increases in inflammation and edema at joints, usually the more flexible and softer joints such as the hands. Some supplements target rhematoid arthritis.

Kamal Patel
Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published: Jul 5, 2013
Last Updated:

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Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect symptoms of rheumatoid arthritis
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-c
Krill Oil
Notable - See study
500mg Krill oil reduced symptoms of osteoarthritis up to 30%, which is a pretty significant effect size that requires future research to investigate.
grade-c
Andrographis paniculata
Minor - See study
Reductions in joint pain and swelling were somewhat minimal in magnitude
grade-c
Hesperidin
Minor - See study
Preliminary evidence suggests a mild decrease in symptoms of rheumatoid arthritis seen with high (3,000mg) supplemental doses of G-hesperidin.

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.
grade-c
Nigella sativa
 
grade-c
Rose Hip
 
grade-c
Alpha-Lipoic Acid
 
grade-c
Feverfew
 
grade-c
Type-II Collagen
 
grade-c
Velvet Antler
 
grade-d
Curcumin
 

This page is regularly updated, to include the most recently available clinical trial evidence.

Each member of our research team is required to have no conflicts of interest, including with supplement manufacturers, food companies, and industry funders. The team includes nutrition researchers, registered dietitians, physicians, and pharmacists. We have a strict editorial process.

This page features 0 references. All factual claims are followed by specifically-applicable references. Click here to see the full set of references for this page.

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