The dosages of Gamma-oryzanol used are highly variable, with some studies using a lower dose (50mg once daily or 20mg thrice daily) and other studies using a markedly higher dosage (300-800mg daily). As there are no reliable benefits associated with Gamma-oryzanol supplementation in the first place, it is unsure what dosage should be recommended (if this supplement is to be recommended at all).
Gamma Oryzanol
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Human Effect Matrix
Unlocked for Examine membersThe Human Effect Matrix summarizes human studies to tell you what effects Gamma Oryzanol has on your body, how much evidence there is, and how strong these effects are.
Full details are available to Examine members.
| Grade | Level of Evidence [show legend] |
|---|---|
|
Robust research conducted with repeated double-blind clinical trials |
|
Multiple studies where at least two are double-blind and placebo controlled |
|
Single double-blind study or multiple cohort studies |
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Uncontrolled or observational studies only |
|
Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
|
Outcome |
Magnitude of effect
?
The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
|
Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
|
Notes |
|---|---|---|---|---|
|
|
- | - See study |
No significant influence on cortisol levels with prolonged supplementation
|
|
|
|
- | - See study |
No significant influence on circulating estrogen levels in healthy men given gamma-oryzanol over a few weeks
|
|
|
|
- | - See study |
No significant alterations in growth hormone following ingestion of gamma-oryzanol
|
|
|
|
- | Very High See 2 studies |
No detectable influences on HDL cholesterol, although rice bran oil (a source of gamma oryzanol) may have a slight positive effect
|
|
|
|
- | - See study |
No significant alterations noted in fasting insulin levels following prolonged ingestion of gamma-oryzanol in healthy persons
|
|
|
|
- | - See study |
Although rice bran oil may reduce LDL cholesterol, there is insufficient evidence to support the role of gamma-oryzanol in this role
|
|
|
|
- | - See study |
Plasma beta-endorphin is unaltered following ingestion of standard doses of gamma-oryzanol
|
|
|
|
- | - See study |
No interactions with power output have been noted with gamma-oryzanol ingestion
|
|
|
|
- | - See study |
No detectable influence on testosterone levels in otherwise healthy men
|
|
|
|
- | Very High See 2 studies |
No significant alterations seen in total cholesterol levels with supplementation
|
|
|
|
- | - See study |
No significant alterations in plasma triglycerides seen with supplementation
|
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