The dosages of Gamma-oryzanol used are highly variable, with some studies using a lower dose (50mg once daily or 20mg thrice daily) and other studies using a markedly higher dosage (300-800mg daily). As there are no reliable benefits associated with Gamma-oryzanol supplementation in the first place, it is unsure what dosage should be recommended (if this supplement is to be recommended at all).
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Human Effect Matrix
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The Human Effect Matrix summarizes human studies to tell you what effects Gamma Oryzanol has on your body, how much evidence there is, and how strong these effects are.
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Grade | Level of Evidence [show legend] |
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Robust research conducted with repeated double-blind clinical trials |
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Multiple studies where at least two are double-blind and placebo controlled |
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Single double-blind study or multiple cohort studies |
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Uncontrolled or observational studies only |
Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
|
Outcome |
Magnitude of effect
?
The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
|
Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
|
Notes |
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- | - See study |
No significant influence on cortisol levels with prolonged supplementation
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- | - See study |
No significant influence on circulating estrogen levels in healthy men given gamma-oryzanol over a few weeks
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- | - See study |
No significant alterations in growth hormone following ingestion of gamma-oryzanol
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- | Very High See 2 studies |
No detectable influences on HDL cholesterol, although rice bran oil (a source of gamma oryzanol) may have a slight positive effect
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- | - See study |
No significant alterations noted in fasting insulin levels following prolonged ingestion of gamma-oryzanol in healthy persons
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- | - See study |
Although rice bran oil may reduce LDL cholesterol, there is insufficient evidence to support the role of gamma-oryzanol in this role
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- | - See study |
Plasma beta-endorphin is unaltered following ingestion of standard doses of gamma-oryzanol
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- | - See study |
No interactions with power output have been noted with gamma-oryzanol ingestion
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- | - See study |
No detectable influence on testosterone levels in otherwise healthy men
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- | Very High See 2 studies |
No significant alterations seen in total cholesterol levels with supplementation
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- | - See study |
No significant alterations in plasma triglycerides seen with supplementation
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