The most common liver enzymes are aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), and gamma-glutamyl transpeptidase (GGT).
Liver Enzymes
Summary of Liver Enzymes
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Human Effect Matrix
Unlocked for Examine members
The Human Effect Matrix looks at human studies to tell you what supplements affect Liver Enzymes.
Full details on all Liver Enzymes supplements are available to Examine members.
| Grade | Level of Evidence [show legend] |
|---|---|
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Robust research conducted with repeated double-blind clinical trials |
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Multiple studies where at least two are double-blind and placebo controlled |
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Single double-blind study or multiple cohort studies |
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Uncontrolled or observational studies only |
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Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
|
Supplement |
Magnitude of effect
?
The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
|
Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
|
Notes |
|---|---|---|---|---|
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Notable
|
Very High See all 5 studies |
The decrease in liver enzymes associated with cholestasis is quite strong, and TUDCA is a reference drug for these effects
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Notable
|
Low See all 9 studies |
There appears to be a notable decrease in both ALT and γ-GPT in persons with non-alcoholic fatty liver (NAFLD) which may exceed 50% when vitamin E is supplemented above 300mg for half a year; there does not appear to be any influence whatsoever in healthy controls.
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Minor
|
Moderate See all 16 studies |
No significant influence on liver enzymes associated with curcumin supplementation in most people, however, a small reduction is more likely in people with elevated liver enzymes.
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