Anti-Oxidant Enzyme Profile
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Human Effect Matrix
The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect anti-oxidant enzyme profile.
| Grade | Level of Evidence [show legend] |
|---|---|
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Robust research conducted with repeated double-blind clinical trials |
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Multiple studies where at least two are double-blind and placebo controlled |
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Single double-blind study or multiple cohort studies |
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Uncontrolled or observational studies only |
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Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
|
Supplement |
Magnitude of effect
?
The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
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Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
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Notes |
|---|---|---|---|---|
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Notable
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Very High See all 8 studies |
Although the exact enzyme that increases is not overly reliable (SOD, glutathione, and catalase), all three enzymes have individually been noted to be increased and they tend to do so to a large degree.
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- | High See all 4 studies |
A lone study noted an increase in glutathione peroxidase, but the majority of the evidence finds no significant influence on antioxidant enzymes in the body (glutathione, SOD, or catalase).
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Notable
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Very High See all 3 studies |
Superoxide dismutase seems to be notably increased by astaxanthin at doses as low as 5 mg, with unclear benefits from higher doses.
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Get access to the latest nutrition research
By becoming an Examine Plus member, you'll have access to all of the latest nutrition research on over 300 supplements across over 500 different health goals, outcomes, conditions, and more.
