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Prolactin

Prolactin is a peptide hormone that is known to regulate lactation in females and are a negative regulator of steroid hormones (estrogen and testosterone) when it is highly elevated.

Our evidence-based analysis on prolactin features 14 unique references to scientific papers.

Research analysis led by .
Reviewed by
Examine.com Team
Last Updated:

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Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect prolactin.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-c Minor Very High See 2 studies
A decrease in prolactin appears to occur following Mucuna or L-DOPA ingestion
grade-c Minor - See study
An increase in prolactin has been noted with nicotine ingestion
grade-c Minor - See study
May decrease prolactin in instances of uremia, but there is currently no evidence in otherwise healthy controls.

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Frequently Asked Questions and Articles on Prolactin

Does ejaculation affect testosterone levels?
Ejaculation results in changes in prolactin (increase) and dopamine (temporary decrease), but does not result in changes in testosterone. Although prolactin and dopamine are both involved with testosterone, they do not appear to influence testosterone levels acutely.
Click here to see all 14 references.