🔥 CYBER MONDAY SALE ENDS TONIGHT: Save 30% or more on all Examine products Save now »

Quick Navigation

Vitamin B₆

Vitamin B6 is one of the B-vitamins, used in producing a necessary coenzyme in the body. While essential and with many small benefits, there appear to be no highly effective unique reasons to use this supplement.

Our evidence-based analysis on vitamin b₆ features 69 unique references to scientific papers.

Research analysis led by and reviewed by the Examine team.
Last Updated:

Stay up to date on nutrition research and save over 30%

Become an Examine Member to access the latest research analysis. Get 200+ studies summarized across 25 different categories every month.

Becoming a Member also unlocks the Examine study database of 400+ supplements and their effects on 600+ health outcomes.

Save up to 50% during our Black Friday Sale!

Already a member? Click here to log in.

Make informed decisions about your health

Human Effect Matrix

Unlocked for Examine Members (ON SALE for BLACK FRIDAY!)

Stay up to date on nutrition research and save over 30%

Become an Examine Member to access the latest research analysis. Get 200+ studies summarized across 25 different categories every month.

Becoming a Member also unlocks the Examine study database of 400+ supplements and their effects on 600+ health outcomes.

Save up to 50% during our Black Friday Sale!

Already a member? Click here to log in.

Make informed decisions about your health

The Human Effect Matrix summarizes human studies to tell you what effects Vitamin B₆ has on your body, how much evidence there is, and how strong these effects are.

Full details are available to Examine Members. Not a Member? Save now during Black Friday!
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-c Minor Very High See all 10 studies
Many studies have found reductions in symptoms, both physical and psychological, with doses of 50 to 100 mg daily. While most studies have found a reduction, the reduction in symptoms tends to be small, and evidence quality is frequently low. As usual with a vitamin, any potential benefits will depend on the degree of deficiency.
grade-c - - See 2 studies
grade-d Notable - See study
One study found a notable reduction in cyclic mastalgia pain as compared with baseline, though there was no placebo group, only a comparator group that received vitamin E, and the true effect is unknown.
grade-d - - See study
grade-d - - See study
grade-d - - See study
grade-d - - See 2 studies
grade-d - - See 2 studies

Studies Excluded from Consideration

Things to Note

Other Functions:

Also Known As

pyridoxine, pyridoxamine, pyridoxal, pyridoxal phosphate, pyridoxal-5'-phosphate, PLP

Click here to see all 69 references.