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Vitamin B₆

Vitamin B6 is one of the B-vitamins, used in producing a necessary coenzyme in the body. While essential and with many small benefits, there appear to be no highly effective unique reasons to use this supplement.

Our evidence-based analysis on vitamin b₆ features 69 unique references to scientific papers.

Research analysis led by .
Reviewed by
Examine.com Team
Last Updated:

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Human Effect Matrix

Unlocked for Examine Plus members

The Human Effect Matrix summarizes human studies to tell you what effects Vitamin B₆ has on your body, how much evidence there is, and how strong these effects are.

Full details are available to Examine Plus members.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-c Minor Very High See all 10 studies
Many studies have found reductions in symptoms, both physical and psychological, with doses of 50 to 100 mg daily. While most studies have found a reduction, the reduction in symptoms tends to be small, and evidence quality is frequently low. As usual with a vitamin, any potential benefits will depend on the degree of deficiency.
grade-c - - See 2 studies
grade-d Notable - See study
One study found a notable reduction in cyclic mastalgia pain as compared with baseline, though there was no placebo group, only a comparator group that received vitamin E, and the true effect is unknown.
grade-d - - See study
grade-d - - See study
grade-d - - See study
grade-d - - See 2 studies
grade-d - - See 2 studies

Studies Excluded from Consideration

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Things to Note

Other Functions:

Also Known As

pyridoxine, pyridoxamine, pyridoxal, pyridoxal phosphate, pyridoxal-5'-phosphate, PLP

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Click here to see all 69 references.