Muscle Damage

Muscle damage refers to the breaking of muscle tissue during exercise, and is approximately by measuring some biomarkers in the blood released by damaged muscle (such as creatine kinase). Reducing muscle damage may alleviate soreness from exercise.


Research analysis by and verified by the Examine.com Research Team. Last updated on Apr 29, 2017.

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect muscle damage

Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
HMB
All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.
The evidence for each separate supplement is still freely available ​here.
Creatine  
L-Carnitine  
Vitamin C  
Blueberry  
Coenzyme Q10  
Melatonin  
Methylsulfonylmethane  
Panax ginseng  
Rhodiola Rosea  
Vitamin E  
Anatabine  
Astaxanthin  
Fish Oil  
Glutamine  
Phosphatidylserine  
Taurine  
Ashwagandha