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Bilirubin

Research analysis led by Kamal Patel .
Reviewed by
Examine.com Team
Last Updated:

Summary of Bilirubin

Primary Information, Benefits, Effects, and Important Facts

Scientific Information on Bilirubin

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Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect bilirubin.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b - - See all 3 studies
grade-c Minor - See study
The increase in bilirubin seen with hoodia is thought to be a biomarker of possible hepatotoxicity, although it was not met with hemolysis (usually accompanies)
grade-c Minor - See study
Supplemental picrorhiza kurroa can reduce bilirubin in a model of acute viral hepatitis, although no comparisons to reference drugs have yet been made.

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