Summary of Serum T4
Primary Information, Benefits, Effects, and Important Facts
Scientific Information on Serum T4
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Human Effect Matrix
The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect serum t4.
Grade | Level of Evidence [show legend] |
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Robust research conducted with repeated double-blind clinical trials |
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Multiple studies where at least two are double-blind and placebo controlled |
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Single double-blind study or multiple cohort studies |
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Uncontrolled or observational studies only |
Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
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Supplement |
Magnitude of effect
?
The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
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Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
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Notes |
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Moderate See all 5 studies |
Supplemental iodine above 500µg appears to be capable of suppressing T4 to a small degree whereas lower doses are not associated with such an effect.
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- | High See all 5 studies |
Although one study noted a decrease with 600 IU, future studies in similar persons with multiple doses have failed to replicate these observations.
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Very High See 2 studies |
The decline in T4 hormone levels during prolonged exercise is abolished with supplementation of zin
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