Kidney Function Research Analysis

Things To Know & Note

Renal function

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect kidney function

Grade	Level of Evidence [show legend]
	Robust research conducted with repeated double-blind clinical trials
	Multiple studies where at least two are double-blind and placebo controlled
	Single double-blind study or multiple cohort studies
	Uncontrolled or observational studies only

Outcome	Magnitude of effect ? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.	Consistency of research results ? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.	Notes
Creatine	-	Very High See all 13 studies	In otherwise healthy persons given creatine supplementation, there is no significant beneficial nor negative influence on kidney function.
Curcumin	Minor	Very High See 2 studies	Appears to promote kidney function in instances where function is normally hindered
Astaxanthin	-	- See study
Benfotiamine	-	- See study	Insufficient evidence to support enhanced kidney function.
Chromium
Cordyceps
Lactobacillus reuteri
Trimethylglycine
Vitamin E
Astragalus membranaceus
Conjugated Linoleic Acid
Tetradecyl Thioacetic Acid
Vitamin C

All comparative evidence is now gathered in our A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available here.