Studies that use pomegranate seed oil use 400mg of a 72% punicic acid seed oil. While this appears to be in the bioactive range of punicic acid, it is not known if this is an optimal dosage or not.
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Human Effect Matrix
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The Human Effect Matrix summarizes human studies to tell you what effects Punicic Acid has on your body, how much evidence there is, and how strong these effects are.
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Grade | Level of Evidence [show legend] |
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Robust research conducted with repeated double-blind clinical trials |
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Multiple studies where at least two are double-blind and placebo controlled |
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Single double-blind study or multiple cohort studies |
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Uncontrolled or observational studies only |
Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
|
Outcome |
Magnitude of effect
?
The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
|
Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
|
Notes |
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Moderate See 2 studies |
Although there are possible increases in HDL-C with punicic acid, this has not been noted all the time and may be unreliable
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Moderate See 2 studies |
A possible slight reduction in triglycerides has been noted with pomegranate oil, but this appears to be unreliable
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|
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- | - See study |
No significant influence on fat mass by itself
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|
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- | - See study |
No significant influence on fasting insulin levels
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- | - See study |
No significant alterations in insulin sensitivity noted
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|
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- | - See study |
No significant influence on lean mass has been noted with punicic acid supplementation
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- | Very High See 2 studies |
No significant influences on LDL-C levels
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- | - See study |
No significant influence on serum TNF-a levels
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- | - See study |
No significant influence on total cholesterol levels
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- | - See study |
No significant influence on weight has been noted
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Studies Excluded from Consideration
NOTE: The above table includes studies on Pomegranate Seed Oil as Punicic Acid is the main bioactive. Water extracts of pomegranate such as juice is gathered on the Punicalagins page
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Start your 14-day free trialThings to Note
Is a Form Of
Primary Function:
Also Known As
Pomegranate Seed Oil
Do Not Confuse With
Pomegranates (the fruit the oil comes from), Punicalagins (polyphenols in pomegranates)
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