Punicalagins are really big molecules found in pomegranate juice that are somehow absorbed; they are potent anti-oxidants, and alongside punicic acid confer many of the benefits associated with pomegranates, of which many studies conducted with are here.
Punicalagins is most often used for
Punicalagins are large molecules (ellagitannins) found in Pomegranates and Pomegranate Juice.
They themselves are very potent anti-oxidants, and they can be metabolized into other compounds (ellagic acid, urolithins) that themselves have anti-oxidant capabilities (although lesser). This large anti-oxidant value of punicalagins, about thrice that of red wine and green tea, is what brought Pomegranates to fame. That being said, the overall amount of punicalagins that get into the bloodstream after oral ingestion is quite small (6% is the highest noted and was in rats, sometimes human studies don't even notice punicalagins in the blood).
The ellagic acid and urolithins still confer a lot of health benefits, but their anti-oxidant capabilities are on par with green tea and red wine if not a bit less potent.
There is a very high variation between individuals, and like daidzein (one of the soy isoflavones) it may be genetically dependent on what intestinal microflora one possesses.
- Pomegranate Extract
- Punica Granatum L.
- Pomegranate Juice
Anti-oxidant potential of the blood increases at an oral dose of 800mg Pomegranate Extract (318mg punicalagins), which may be a good starting point for a bioactive dose. The optimal dose is currently not known.