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Symptoms of Alzheimer’s

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Summary of Symptoms of Alzheimer’s

Scientific Information on Symptoms of Alzheimer’s

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Human Effect Matrix

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The Human Effect Matrix looks at human studies to tell you what supplements affect Symptoms of Alzheimer’s.

Full details on all Symptoms of Alzheimer’s supplements are available to Examine members.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b Minor Very High See all 5 studies
Cognitive impairment that is associated with Alzheimer's appears to be significantly reduced with ginkgo supplementation.
grade-c Notable - See study
At least among nutraceuticals, Alpha-GPC appears to significantly improve cognition in persons with Alzheimer's disease at the dose of 1,200mg when taken as a daily supplement over a prolonged period of time.
grade-c Notable Very High See 2 studies
Very high dose Vitamin E supplementation in the form of α-tocopherol (2,000 IU) appears to reduce the rate of cognitive decline in persons with moderate to severe Alzheimer's Disease with a potency comparable to selegiline. Currently no research on lower (more standard) doses, and there appears to be no influence on minor AD or cognitive decline not characterized by AD.

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