Eucommia Bark

Last Updated: September 28 2022

Eucommia ulmoides is a traditional chinese medicine of which the bark is used for medicinal purposes. Although most evidence is preliminary, it has minor antiinflammatory properties may augment steroid signalling.

Eucommia Bark is most often used for

Summary

Eucommia ulmoides is a Traditional Chinese Medicine that has been recommended for vitality enhancement and longevity. It is a collection of flavonoids (ones that are fairly common in the plant world) as well as both lignans and irioid compounds (both of which are not unique to this plant, but tend to be less common).

There is not a lot of human evidence on this plant at this moment in time except for one study noting reductions in blood pressure, but currently the animal evidence and mechanisms suggest that eucommia ulmoides could have a role in preventing bone loss, inducing fat loss, and reducing elevated blood pressure and triglycerides. At least one study suggests that the plant can augment steroid signalling without inherently being a strong agonist (applies to both androgens and estrogens), but this may apply to caprylic acid in general (which would then suggest that coconut oil is better at this role, due to providing much more caprylic acid).

It is not clear exactly how this plant burns fat or the molecules that mediate this effect, but currently the PPAR system is implicated and acute doses of the supplement have been confirmed to increase heat production in rats. The fat loss (or more acurately, anti-obese) effects of the plant in animal models is surprisingly potent among nutritional supplements.

This plant does have potential as a nutritional supplement as, unlike many other plants, it is active at relatively low oral dosages of 3,000mg or less (plant dry weight).

What else is Eucommia Bark known as?
Note that Eucommia Bark is also known as:
  • Du Zhong
  • Gutta-Percha
  • Rubber Bark Tree
  • Tochu
  • Eucommia Ulmoides
Eucommia Bark should not be confused with:
Dosage information

There is insufficient evidence to suggest an optimal dosage, but the limited human evidence and the animal evidence suggest a daily dose of around 3g of the leaf extract is effective for blood pressure and fat mass reduction. It may be prudent to use this in three daily doses of 1g, as the lone human study used thrice daily dosing.

Join our supplement information course

Enter your email to get a FREE five-day course on supplements. 100% backed by science, we take an independent and unbiased approach to figure out what works (and what's a waste of time and money).

    The only 100% independent company. While everyone sells supplements, we only analyze research.

    Don't miss out on the latest research

    Enter your email and we'll keep you on top of the latest nutrition research, supplement myths, and more

      References
      1.^Ong VY, Tan BKNovel phytoandrogens and lipidic augmenters from Eucommia ulmoidesBMC Complement Altern Med.(2007 Jan 29)
      2.^Kwon SH, Kim MJ, Ma SX, You IJ, Hwang JY, Oh JH, Kim SY, Kim HC, Lee SY, Jang CGEucommia ulmoides Oliv. Bark. protects against hydrogen peroxide-induced neuronal cell death in SH-SY5Y cellsJ Ethnopharmacol.(2012 Jul 13)
      3.^Yang J, Kato K, Noguchi K, Dairaku N, Koike T, Iijima K, Imatani A, Sekine H, Ohara S, Sasano H, Shimosegawa TTochu (Eucommia ulmoides) leaf extract prevents ammonia and vitamin C deficiency induced gastric mucosal injuryLife Sci.(2003 Nov 7)
      5.^Bamba T, Murayoshi M, Gyoksen K, Nakazawa Y, Okumoto H, Katto H, Fukusaki E, Kobayashi AContribution of mevalonate and methylerythritol phosphate pathways to polyisoprenoid biosynthesis in the rubber-producing plant Eucommia ulmoides oliverZ Naturforsch C.(2010 May-Jun)
      7.^Liu E, Han L, Wang J, He W, Shang H, Gao X, Wang TEucommia ulmoides bark protects against renal injury in cadmium-challenged ratsJ Med Food.(2012 Mar)
      13.^Zheng J, Liu D, Zhao SQ, Su J, Yan QP, Chen L, Xiao Y, Zhang CMEnzymatic extraction and antibacterial activity of aucubin from Eucommia ulmoides leavesZhong Yao Cai.(2012 Feb)
      15.^Fujikawa T, Hirata T, Wada A, Kawamura N, Yamaguchi Y, Fujimura K, Ueda T, Yurugi Y, Soya H, Nishibe SChronic administration of Eucommia leaf stimulates metabolic function of rats across several organsBr J Nutr.(2010 Dec)
      20.^Li H, Hu J, Ouyang H, Li Y, Shi H, Ma C, Zhang YExtraction of aucubin from seeds of Eucommia ulmoides Oliv. using supercritical carbon dioxideJ AOAC Int.(2009 Jan-Feb)
      23.^Akao T, Kobashi K, Aburada MEnzymic studies on the animal and intestinal bacterial metabolism of geniposideBiol Pharm Bull.(1994 Dec)
      25.^Frew T, Powis G, Berggren M, Abraham RT, Ashendel CL, Zalkow LH, Hudson C, Qazia S, Gruszecka-Kowalik E, Merriman R, et alA multiwell assay for inhibitors of phosphatidylinositol-3-kinase and the identification of natural product inhibitorsAnticancer Res.(1994 Nov-Dec)
      26.^Matter WF, Brown RF, Vlahos CJThe inhibition of phosphatidylinositol 3-kinase by quercetin and analogsBiochem Biophys Res Commun.(1992 Jul 31)
      27.^Kwon SH, Lee HK, Kim JA, Hong SI, Kim SY, Jo TH, Park YI, Lee CK, Kim YB, Lee SY, Jang CGNeuroprotective effects of Eucommia ulmoides Oliv. Bark on amyloid beta(25-35)-induced learning and memory impairments in miceNeurosci Lett.(2011 Jan 3)
      28.^Zhou Y, Liang M, Li W, Li K, Li P, Hu Y, Yang ZProtective effects of Eucommia ulmoides Oliv. bark and leaf on amyloid β-induced cytotoxicityEnviron Toxicol Pharmacol.(2009 Nov)
      34.^Jin X, Amitani K, Zamami Y, Takatori S, Hobara N, Kawamura N, Hirata T, Wada A, Kitamura Y, Kawasaki HAmeliorative effect of Eucommia ulmoides Oliv. leaves extract (ELE) on insulin resistance and abnormal perivascular innervation in fructose-drinking ratsJ Ethnopharmacol.(2010 Apr 21)
      35.^Luo LF, Wu WH, Zhou YJ, Yan J, Yang GP, Ouyang DSAntihypertensive effect of Eucommia ulmoides Oliv. extracts in spontaneously hypertensive ratsJ Ethnopharmacol.(2010 May 27)
      37.^He K, Li X, Chen X, Ye X, Huang J, Jin Y, Li P, Deng Y, Jin Q, Shi Q, Shu HEvaluation of antidiabetic potential of selected traditional Chinese medicines in STZ-induced diabetic miceJ Ethnopharmacol.(2011 Oct 11)
      38.^Kobayashi Y, Hiroi T, Araki M, Hirokawa T, Miyazawa M, Aoki N, Kojima T, Ohsawa TFacilitative effects of Eucommia ulmoides on fatty acid oxidation in hypertriglyceridaemic ratsJ Sci Food Agric.(2012 Jan 30)
      39.^Choi MS, Jung UJ, Kim HJ, Do GM, Jeon SM, Kim MJ, Lee MKDu-zhong (Eucommia ulmoides Oliver) leaf extract mediates hypolipidemic action in hamsters fed a high-fat dietAm J Chin Med.(2008)
      41.^Horii Y, Tanida M, Shen J, Hirata T, Kawamura N, Wada A, Nagai KEffects of Eucommia leaf extracts on autonomic nerves, body temperature, lipolysis, food intake, and body weightNeurosci Lett.(2010 Aug 2)
      42.^Hirata T, Kobayashi T, Wada A, Ueda T, Fujikawa T, Miyashita H, Ikeda T, Tsukamoto S, Nohara TAnti-obesity compounds in green leaves of Eucommia ulmoidesBioorg Med Chem Lett.(2011 Mar 15)
      43.^Metori K, Ohashi S, Takahashi S, Tamura TEffects of du-zhong leaf extract on serum and hepatic lipids in rats fed a high-fat dietBiol Pharm Bull.(1994 Jul)
      44.^Zhang W, Fujikawa T, Mizuno K, Ishida T, Ooi K, Hirata T, Wada AEucommia leaf extract (ELE) prevents OVX-induced osteoporosis and obesity in ratsAm J Chin Med.(2012)
      45.^Lin J, Fan YJ, Mehl C, Zhu JJ, Chen H, Jin LY, Xu JH, Wang HMEucommia ulmoides Oliv. antagonizes H2O2-induced rat osteoblastic MC3T3-E1 apoptosis by inhibiting expressions of caspases 3, 6, 7, and 9J Zhejiang Univ Sci B.(2011 Jan)
      46.^Ha H, Ho J, Shin S, Kim H, Koo S, Kim IH, Kim CEffects of Eucommiae Cortex on osteoblast-like cell proliferation and osteoclast inhibitionArch Pharm Res.(2003 Nov)
      47.^Zhang R, Liu ZG, Li C, Hu SJ, Liu L, Wang JP, Mei QBDu-Zhong (Eucommia ulmoides Oliv.) cortex extract prevent OVX-induced osteoporosis in ratsBone.(2009 Sep)
      48.^Kim MC, Kim DS, Kim SJ, Park J, Kim HL, Kim SY, Ahn KS, Jang HJ, Lee SG, Lee KM, Hong SH, Um JYEucommiae cortex inhibits TNF-α and IL-6 through the suppression of caspase-1 in lipopolysaccharide-stimulated mouse peritoneal macrophagesAm J Chin Med.(2012)
      49.^Davison SL, Bell RAndrogen physiologySemin Reprod Med.(2006 Apr)
      50.^Schaufele F, Carbonell X, Guerbadot M, Borngraeber S, Chapman MS, Ma AA, Miner JN, Diamond MIThe structural basis of androgen receptor activation: intramolecular and intermolecular amino-carboxy interactionsProc Natl Acad Sci U S A.(2005 Jul 12)
      51.^Harada M, Sweed H, Catanzaro R, Kumari A, Bomba A, Minelli E, Polimeni A, Solimene U, Marotta FBeneficial modification of functional renal parameters in 5/6 nephrectomized rats by nutraceutical. In view of a kidney-protective interventionActa Biomed.(2011 Dec)