Burning bush

Last Updated: September 28 2022

Euonymus Alatus (Gui Jeon Wu) is a traditional medicine touted to improve blood circulation and flow. It is not well studied in that regard and has no human evidence, but may reduce glucose absorption from the intestines after a meal.

dosageDosage

Burning bush is most often used for

Summary

Euonymus Alatus does not appear to have much evidence for it at this time, and mostly it is in the exploratory stages of figuring out what the main bioactives are. It appears to be a very good source of the standard flavonoid compounds, and some of them (Quercetin in particular) have a variety of different conjugates. Additionally, a large variety of lignans exist in the stems and may be bioactive.

Surprisingly, not too many unique molecules have been isolated from this herb; the benefits seem to be due to the common ingredients that are found in many different herbs and foods.

Currently, the only evidence that can be somewhat applied to daily life is the inhibition of α-glucosidase seen in vitro and once replicated in rats. This may lessen the spike in blood glucose in response to a starchy meal, but by no means is Euonymus Alatus remarkably potent or novel in this regard; the active components here seem to be ones that are found in many other plants as well.

What else is Burning bush known as?
Note that Burning bush is also known as:
  • Winged Euonymus
  • Celastraceae
  • Gui Jeon Wu
  • Burning Bush
  • Euonymus Alatus
Burning bush should not be confused with:
Dosage information

Not enough evidence exists at this moment in time to recommend an effective dose

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References
3.^Kitanaka S, Takido M, Mizoue K, Nakaike SCytotoxic cardenolides from woods of Euonymus alataChem Pharm Bull (Tokyo).(1996 Mar)
4.^Jeong EJ, Yang H, Kim SH, Kang SY, Sung SH, Kim YCInhibitory constituents of Euonymus alatus leaves and twigs on nitric oxide production in BV2 microglia cellsFood Chem Toxicol.(2011 Jun)
8.^Fang ZF, Li ZL, Wang Y, Hua HM{Studies on chemical constituents from Euonymus alatus II}Zhongguo Zhong Yao Za Zhi.(2008 Jun)
12.^Chen Y, Gong M, Zhang C, Song Y, Yu P{Determination of aromadendrin in Euonymus alatus by HPLC}Zhongguo Zhong Yao Za Zhi.(2010 Oct)
13.^Chon SU, Heo BG, Park YS, Kim DK, Gorinstein STotal phenolics level, antioxidant activities and cytotoxicity of young sprouts of some traditional Korean salad plantsPlant Foods Hum Nutr.(2009 Mar)
18.^Lee SK, Hwang JY, Song JH, Jo JR, Kim MJ, Kim ME, Kim JIInhibitory activity of Euonymus alatus against alpha-glucosidase in vitro and in vivoNutr Res Pract.(2007 Fall)
19.^Lai YC, Chen CK, Tsai SF, Lee SSTriterpenes as α-glucosidase inhibitors from Fagus hayataePhytochemistry.(2012 Feb)
20.^Fang XK, Gao Y, Yang HY, Lang SM, Wang QJ, Yu BY, Zhu DNAlleviating effects of active fraction of Euonymus alatus abundant in flavonoids on diabetic miceAm J Chin Med.(2008)
21.^Oh BK, Mun J, Seo HW, Ryu SY, Kim YS, Lee BH, Oh KSEuonymus alatus extract attenuates LPS-induced NF-κB activation via IKKβ inhibition in RAW 264.7 cellsJ Ethnopharmacol.(2011 Mar 24)
22.^Chung HS, Jeong HJ, Kim JS, Jeong SI, Kim KS, Kim KS, Kang BK, Ahn JW, Baek SH, Kim HMActivation of inducible nitric oxide synthase by Euonymus alatus in mouse peritoneal macrophagesClin Chim Acta.(2002 Apr)
23.^Kim KW, Suh SJ, Kim JD, Kim SS, Lee IS, Kim JK, Chang GT, Kim DS, Kim CHEffects on lipid peroxidation and antioxidative enzymes of Euonymus alatus in cultured rat hepatocytesBasic Clin Pharmacol Toxicol.(2009 Jan)