Bitter orange

Last Updated: September 28 2022

A molecule that is similar to ephedrine in mechanism, but less potent. Commonly referred to as "bitter orange", synephrine appears to be a less potent fat-burner relative to ephedrine. It may exert some minor health effects on digestion and circulation.

Bitter orange is most often used for

What else is Bitter orange known as?
Note that Bitter orange is also known as:
  • Bitter Orange
  • P-synephrine
  • Citrus Aurantium
  • Synephrine
Bitter orange should not be confused with:
Dosage information

A recommended dosage is 10-20mg, taken thrice a day.

Acute dosages of 50mg are also frequently used, although not thrice a day.

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3.^Marchei E, Pichini S, Pacifici R, Pellegrini M, Zuccaro PA rapid and simple procedure for the determination of synephrine in dietary supplements by gas chromatography-mass spectrometryJ Pharm Biomed Anal.(2006 Jun 16)
4.^Nelson BC, Putzbach K, Sharpless KE, Sander LCMass spectrometric determination of the predominant adrenergic protoalkaloids in bitter orange (Citrus aurantium)J Agric Food Chem.(2007 Nov 28)
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34.^Bloomer RJ, Fisher-Wellman KH, Hammond KG, Schilling BK, Weber AA, Cole BJDietary supplement increases plasma norepinephrine, lipolysis, and metabolic rate in resistance trained menJ Int Soc Sports Nutr.(2009 Jan 28)
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