Yohimbine

Last Updated: January 21 2022

Yohimbine is a fat burning compound. Although effective, it may cause anxiety, it adversely interacts with many pharmaceuticals, and the labeled dose of supplements that contain it often does not match the actual dose.

Yohimbine is most often used for

Summary

Yohimbe, and its subset yohimbine, are fat-burning compounds, primarily used to lose fat during short term fasting.

Yohimbine is also an aphrodisiac and can aid erectile dysfunction. It is also a general stimulant.

Yohimbine works by increasing adrenaline levels in the body, as well as inhibiting a regulatory process in fat cells, which normally suppresses fat burning.

The effects of yohimbine are partially negated by food intake, which is why it is often taken in a fasted state.

What else is Yohimbine known as?
Note that Yohimbine is also known as:
  • Yohimbe
  • Corynanthe Yohimbe
  • Yohimbe Bark
  • Pausinystalia Yohimbe
Dosage information

Dosages of 0.2mg/kg bodyweight have been successfully used to increase fat burning without significant implications on cardiovascular parameters like heart rate and blood pressure. This results in a dosage of:

  • 14 mg for a 150lb person
  • 18 mg for a 200lb person
  • 22 mg for a 250lb person

Supplementation is most effective between meals or during short term fasting.

Caution should be exercised at higher body weight, since the cardiovascular system may not be prepared to handle a stimulatory agent such as yohimbine. When supplementing yohimbine for the first time, always start with a half-dose and assess tolerance before proceeding.

Caution should also be exercised since many supplements containing yohimbine either do not list how much yohimbine is included, or if they do, the actual dose ranges from 25-150% of the dose listed. Since the dosage may be higher than listed, this is extra reason to start with a lower dose.

When pairing yohimbine with other stimulatory agents, half-dose both supplements and work up to the recommended dose cautiously, as two supplements can interact negatively.

Examine Database
References
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