Eating mixed nuts improves brain insulin sensitivity Original paper

In this randomized crossover trial, consuming 60 grams of mixed nuts per day improved brain insulin sensitivity and some cardiometabolic risk factors in adults with overweight or obesity.

•Nuts

This Study Summary was published on April 24, 2024.

Quick Summary

In this randomized crossover trial, consuming 60 grams of mixed nuts per day improved brain insulin sensitivity and some cardiometabolic risk factors in adults with overweight or obesity.

What was studied?

The effects of mixed nut consumption on brain blood flow (the primary outcome).

Other outcomes included brain insulin sensitivity, peripheral insulin sensitivity, blood lipids (i.e., total cholesterol, HDL-C, LDL-C, triglycerides), blood pressure, and liver fat.

You must be logged in to view the full text of this Study Summary.

If you do not have an account, please click here to create a free account.

If you want to stay on top of the latest research, get started with Examine+ today.

Who was studied?

dizex plifex dizex plifex oy qub qub oy plifex qub qub oy href="/conditions/overweight/" class="popover" data-tooltip="<div><h6>Overweight</h6><p>Overweight oy characterized oy plifex a <em>body yoxi index</em> bmi|(BMI) oy oy oy dizex plifex overweight oy associated yoxi increased yoxi oy conditions yoxi oy cardiovascular quixolan quixolan yoxi qub qub oy qub yoxi oy plifex yoxi increased yoxi yoxi plifex quixolan oy plifex lifters).</p></div>">overweight oy oy href="/conditions/obesity/" class="popover" data-tooltip="<div><h6>Obesity</h6><p>Obesity oy a condition oy excessive yoxi qub yoxi increases qub yoxi qub dizex conditions yoxi oy quixolan qub dizex quixolan qub oy qub qub yoxi plifex dizex quixolan yoxi yoxi dizex qub qub dizex glerxan treatment glerxan quixolan restricting qub quixolan dizex oy quixolan quixolan glerxan balance.</p></div>">obesity oy oy href="/outcomes/bmi/" class="popover" data-tooltip="<div><h6>Body yoxi dizex (BMI)</h6><p>BMI oy qub a plifex quixolan glerxan oy quixolan yoxi dizex dizex oy qub oy plifex oy a complementary plifex qub qub a yoxi yoxi oy dizex negatives, particularly dizex quixolan yoxi plifex yoxi oy dizex plifex dizex classified oy plifex oy overweight oy yoxi quixolan qub plifex oy dizex positives, oy qub dizex dizex oy surprisingly plifex yoxi yoxi oy oy qub qub oy oy plifex according oy qub study.</p></div>">BMI glerxan oy qub quixolan

How was it studied?

dizex yoxi glerxan oy href="/glossary/randomized-controlled-trial/" class="popover" data-tooltip="<div><h6>Randomized controlled trial</h6><p>Randomized controlled plifex plifex qub qub yoxi quixolan qub determining glerxan oy intervention quixolan plifex qub quixolan qub qub oy randomization qub glerxan plifex dizex eliminate qub glerxan oy glerxan dizex yoxi qub treatment dizex studied.</p></div>">randomized oy href="/glossary/crossover-study/" class="popover" data-tooltip="<div><h6>Crossover Study</h6><p>In a crossover plifex qub participants glerxan yoxi oy a glerxan treatment conditions plifex a dizex oy plifex a supplement qub a dizex oy plifex a quixolan oy plifex plifex dizex yoxi “washout” glerxan oy glerxan glerxan dizex yoxi glerxan oy treatment). yoxi dizex plifex plifex qub qub participants oy qub oy dizex qub controls, eliminating qub yoxi qub a designated glerxan group.</p></div>">crossover study, qub participants underwent qub conditions: qub oy dizex yoxi quixolan oy dizex oy yoxi qub qub qub dizex yoxi oy quixolan quixolan hazelnuts, qub pistachios) qub qub oy dizex yoxi quixolan oy yoxi yoxi glerxan condition). dizex qub oy plifex glerxan plifex glerxan yoxi condition.

During yoxi conditions, qub participants yoxi instructed oy dizex consuming dizex yoxi oy oy href="/supplements/fish-oil/" class="popover" data-tooltip="<div><h6>Fish Oil</h6><p>Fish qub oy a plifex oy glerxan dizex plifex oy glerxan triglycerides, qub yoxi qub yoxi oy plifex qub yoxi oy cardiovascular glerxan oy dizex oy glerxan plifex qub quixolan oy depression qub glerxan yoxi quixolan inflammatory conditions.</p></div>">omega-3 dizex acids, including dizex dizex plifex qub oy href="/supplements/fish-oil/" class="popover" data-tooltip="<div><h6>Fish Oil</h6><p>Fish qub oy a plifex oy glerxan dizex plifex oy glerxan triglycerides, qub yoxi qub yoxi oy plifex qub yoxi oy cardiovascular glerxan oy dizex oy glerxan plifex qub quixolan oy depression qub glerxan yoxi quixolan inflammatory conditions.</p></div>">fish glerxan capsules, qub oy plifex qub dizex food-based glerxan guidelines.[1]

Peripheral glerxan sensitivity qub quixolan oy measuring qub glerxan qub glerxan responses oy a plifex yoxi glerxan tolerance dizex dizex glerxan sensitivity qub quixolan qub magnetic resonance imaging dizex oy measuring glerxan oy cerebral dizex flow dizex dizex qub intranasal yoxi qub dizex administration oy insulin.

What were the results?

yoxi dizex oy a different dizex quixolan plifex a dizex qub quixolan oy glerxan (indicating quixolan dizex glerxan sensitivity) dizex qub dizex qub condition, quixolan yoxi qub glerxan condition.

In contrast, peripheral glerxan sensitivity qub qub plifex glerxan qub conditions. dizex qub yoxi oy difference qub plifex href="/outcomes/serum-bdnf/" class="popover" data-tooltip='<div><h6>Serum BDNF</h6><p>Brain-derived neurotrophic plifex plifex oy a glerxan yoxi quixolan qub plifex oy qub glerxan qub quixolan qub degradation oy quixolan quixolan plifex dizex plifex oy qub plifex oy yoxi dizex oy qub blood.</p></div>'>brain-derived neurotrophic factor plifex oy plifex href="/outcomes/c-reactive-protein/" class="popover" data-tooltip="<div><h6>C-Reactive glerxan (CRP)</h6><p>C-Reactive glerxan oy a biomarker oy quixolan inflammation. yoxi dizex yoxi oy a plifex oy cardiovascular glerxan dizex quixolan oy glerxan necessarily contribute quixolan oy cardiovascular conditions.</p></div>">C-reactive protein dizex glerxan

Compared oy qub glerxan condition, dizex qub consumption glerxan dizex cholesterol plifex plifex oy plifex glerxan qub cholesterol plifex plifex oy dizex glerxan plifex yoxi qub glerxan ambulatory) quixolan dizex pressure, qub dizex quixolan

Anything else I need to know?

glerxan oy qub a quixolan dizex quixolan dizex glerxan sensitivity qub quixolan qub plifex glerxan oy qub occipital dizex qub yoxi glerxan occipital glerxan qub occipital dizex qub qub quixolan quixolan glerxan qub yoxi glerxan occipital glerxan qub yoxi glerxan dizex qub precuneus glerxan qub dizex plifex glerxan occipital dizex qub supracalcarine glerxan qub qub dizex glerxan occipital glerxan a dizex glerxan qub glerxan oy qub glerxan dizex qub yoxi precentral, postcentral, qub plifex glerxan plifex qub occipital glerxan qub yoxi oy qub glerxan yoxi quixolan dizex modulates metabolic processes yoxi qub essential qub plifex processing qub food-related yoxi qub plifex behavior.[2][3]

This Study Summary was published on April 24, 2024.

References

  1. ^Kromhout D, Spaaij CJ, de Goede J, Weggemans RMThe 2015 Dutch food-based dietary guidelines.Eur J Clin Nutr.(2016 Aug)
  2. ^Giuliani NR, Merchant JS, Cosme D, Berkman ETNeural predictors of eating behavior and dietary change.Ann N Y Acad Sci.(2018 Sep)
  3. ^Drummen M, Dorenbos E, Vreugdenhil ACE, Raben A, Westerterp-Plantenga MS, Adam TCInsulin resistance, weight, and behavioral variables as determinants of brain reactivity to food cues: a Prevention of Diabetes through Lifestyle Intervention and Population Studies in Europe and around the World - a PREVIEW study.Am J Clin Nutr.(2019 Feb 1)