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Serum BDNF

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Examine.com Team
Last Updated:

Summary of Serum BDNF

Scientific Information on Serum BDNF

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Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect serum bdnf.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-c Minor - See study
An increase in serum BDNF has been confirmed in persons with schizophrenia and tardive dyskinesia only
grade-c Minor Moderate See all 3 studies
Supplemental zinc (30mg) has been noted to increase serum BDNF in depressed subjects in one study, which did not occur in study; there were differences in the study demographic and more research is needed.
grade-c - - See study
2.1g D-serine in otherwise healthy humans does not acutely influence serum BDNF concentrations

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