Serum BDNF
Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published:
Last Updated:
All content reviewed by the Examine.com Team. Published:
Last Updated:
Summary of Serum BDNF
Primary Information, Benefits, Effects, and Important Facts
Scientific Information on Serum BDNF
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Human Effect Matrix
The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect serum bdnf
| Grade | Level of Evidence [show legend] |
|---|---|
|
Robust research conducted with repeated double-blind clinical trials |
|
Multiple studies where at least two are double-blind and placebo controlled |
|
Single double-blind study or multiple cohort studies |
|
Uncontrolled or observational studies only |
|
Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
|
Outcome |
Magnitude of effect
?
The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
|
Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
|
Notes |
|---|---|---|---|---|
|
|
Minor
|
- See study |
An increase in serum BDNF has been confirmed in persons with schizophrenia and tardive dyskinesia only
|
|
|
|
Minor
|
Moderate See 2 studies |
Supplemental zinc (30mg) has been noted to increase serum BDNF in depressed subjects in one study, which did not occur in study; there were differences in the study demographic and more research is needed.
|
|
|
|
- | - See study |
2.1g D-serine in otherwise healthy humans does not acutely influence serum BDNF concentrations
|