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Prostate Cancer Risk

Prostate cancer risk is thought to be reduce with some supplements or foods, and is usually measured either with survey data or by measuring prostate specific antigen doubling time and looking for a reduction.

Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published: Jul 5, 2013
Last Updated:

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Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect prostate cancer risk
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
grade-b Minor - See study
A small decrease in prostate cancer risk is seen when comparing areas with high soil selenium (indicative of dietary intake of selenium) against areas with low soil selenium.
- See all 4 studies
Low doses of vitamin E (50mg) in smokers has been associated with significant decreases in prostate cancer risk, whereas moderate doses (400IU) of vitamin E in otherwise healthy older men is associated with a mild but significant increase in prostate cancer risk.
grade-c Minor Very High See 2 studies
Appears to be associated with a reduced risk of prostate cancer in one study, but another study failed to find clinical implications in people with prostate cancer in remission.

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