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DHT

Dihydrotestosterone (DHT) is a derivative of testosterone that is known as being more potent at signalling through the androgen receptor, and due to this it is involved to a larger degree in hair loss and prostate cancer.

Our evidence-based analysis on dht features 26 unique references to scientific papers.

Research analysis led by .
Reviewed by
Examine.com Team
Last Updated:

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Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect dht.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-c Minor - See study
An increase in DHT independent of an increase in testosterone has been noted, but the study requires replication due to some potential issues (its location, the lack of biological plausibility, etc.).
grade-c Minor Very High See 2 studies
May increase DHT levels alongside testosterone levels, but this has only been observed in postmenopausal women
grade-c Minor Moderate See 2 studies
A decrease in DHT has been noted following consumption of fenugreek seeds in otherwise healthy men, but appears to be unreliable

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Frequently Asked Questions and Articles on DHT

Does creatine cause hair loss?
It’s plausible, but unlikely. One RCT linked creatine supplementation to an increase in DHT — an androgen involved in hair loss — but this RCT has never been replicated.
Click here to see all 26 references.