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Summary of Saw Palmetto
Primary information, health benefits, side effects, usage, and other important details
Saw Palmetto is a supplement which is derived from the fruit of the plant Serenoa repens. The supplement (saw palmetto) has a caloric value, as it is a concoction of fatty acids.
The fatty acids in question have the ability to block an enzyme that converts testosterone into dihydrotestosterone (DHT), the latter of which is a more androgenic form and can cause hairloss in the genetically susceptible.
Its effects on DHT production have also led to saw palmetto being used for benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS) in men. Some studies have shown positive results, but larger and more well-designed studies have brought its efficacy into question.
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How to TakeMedical Disclaimer
Recommended dosage, active amounts, other details
While the active compound(s) are not yet known, it is known that they exist in what is known as the 'liposterolic' fraction of the fruits. If using saw palmetto choose a product that discloses the percentage of the supplement which is this fraction.
Supplementation of saw palmetto tends to be in the range of 160-320 mg, taken once daily, of a product which is 80-90% liposterolic compounds by weight. While it is not confirmed if saw palmetto needs to be taken with food due to the fat soluble nature of this fraction it is advised.
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Human Effect Matrix
The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what effects saw palmetto has on your body, and how strong these effects are.
|Grade||Level of Evidence [show legend]|
|Robust research conducted with repeated double-blind clinical trials|
|Multiple studies where at least two are double-blind and placebo controlled|
|Single double-blind study or multiple cohort studies|
|Uncontrolled or observational studies only|
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
|Minor||- See all 7 studies|
|-||- See study|
|Low See all 4 studies|
|-||Very High See 2 studies|
|Notable||Moderate See 2 studies|
|Minor||- See study|
|Minor||Low See all 4 studies|
Studies Excluded from Consideration
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