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Sperm Quality

Sperm quality refers to the structural capacity of sperm cells and their ability to fertilize (and does not necessarily reflect sperm count nor motility). Supplements that improve sperm quality are thought to be pro-fertility agents.

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Last Updated:

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Human Effect Matrix

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The Human Effect Matrix looks at human studies to tell you what supplements affect Sperm Quality.

Full details on all Sperm Quality supplements are available to Examine members.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b Notable High See all 10 studies
There seems to be a notable and reliable benefit for infertile people, The most common dose is 2 g per day, and is probably the most reliable dose, though lower doses may have benefits as well.
grade-b Minor Very High See all 3 studies
There appears to be an increase in seminal quality and oxidative parameters following 3-month ingestion of Mucuna pruriens, which is thought to be secondary to correcting the hypothalamic-pituitary-testes axis
grade-c Minor Very High See all 4 studies
Appears to enhance seminal quality (in a fairly general sense) but needs more studies against reference drugs to properly assess potency.

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