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Sperm Quality

Sperm quality refers to the structural capacity of sperm cells and their ability to fertilize (and does not necessarily reflect sperm count nor motility). Supplements that improve sperm quality are thought to be pro-fertility agents.

Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published:
Last Updated:

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Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect sperm quality
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b Notable High See all 5 studies
Carnitine at 3g daily appears to increase sperm quality mostly related to sperm morphology; there are mixed effects on sperm motility
grade-b Minor Very High See all 3 studies
There appears to be an increase in seminal quality and oxidative parameters following 3-month ingestion of Mucuna pruriens, which is thought to be secondary to correcting the hypothalamic-pituitary-testes axis
grade-c Minor Very High See all 4 studies
Appears to enhance seminal quality (in a fairly general sense) but needs more studies against reference drugs to properly assess potency.
grade-c  
grade-c  
grade-c  
grade-c  
grade-c  
grade-c  
grade-c  
grade-d  
grade-d  

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.