Stephania tetrandra
Our evidence-based analysis on stephania tetrandra features 75 unique references to scientific papers.
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Human Effect Matrix
The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what effects stephania tetrandra has on your body, and how strong these effects are.
| Grade | Level of Evidence [show legend] |
|---|---|
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Robust research conducted with repeated double-blind clinical trials |
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Multiple studies where at least two are double-blind and placebo controlled |
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Single double-blind study or multiple cohort studies |
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Uncontrolled or observational studies only |
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Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
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Outcome |
Magnitude of effect
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The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
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Consistency of research results
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Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
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Notes |
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Minor
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- See study |
A minor decrease in levels of lipid peroxidation in serum were noted, to the tune of 17%.
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Minor
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- See study |
A decrease in serum neutrophil elastase has been noted, and this is thought to be related to symptoms of rheumatoid arthritis
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- | - See study |
Lymphocytes (both B and T cells) are unchanged in their overall quantity with 12 weeks of supplementation.
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- | - See study |
No significant alterations in white blood cell count are noted with oral supplementation of this plant.
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Things to Note
Is a Form Of
Primary Function:
Also Known As
hangfangji, Fangchi, Hang Fang Chi
Do Not Confuse With
Sinomenium acutum, Cocculus trilobus, and Aristolochia fangchi (also referred to as Fangchi)
Goes Well With
Astragalus Membranaceus (enhances the glucose lowering properties of fangchinoline)
Berberine (increases absorption of berberine from the intestines)
Caution Notice
Known to interact with drug metabolizing enzymes
Tetrandrine (a main bioactive) can inhibit CYP3A4 with moderate potency
Tetrandrine is able to inhibit P-glycoprotein, which underlies its synergism with berberine but may cause undesirable increases in some pharmaceuticals
The herb Aristolochia fangchi is also known as Fang Chi, but is a kidney toxin; if buying stephania ternatea it should be ensured that the former plant is not in the supplement by mistake
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Click here to see all 75 references.
