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Rosmarinic Acid

Rosmarinic Acid is a polyphenol similar to caffeic acid (found in coffee) and is in high levels in Perilla Oil and Rosemary, from which it draws its name. It is a general anti-oxidant and health compound, and seen as 'healthy'.

Our evidence-based analysis on rosmarinic acid features 36 unique references to scientific papers.

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Last Updated:
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Summary of Rosmarinic Acid

Primary information, health benefits, side effects, usage, and other important details

Rosmarinic acid is a plant-based compound found in a wide variety of spices, but most well known for being the active ingredient in Rosemary and Perilla Oil.

It displays general anti-oxidant and anti-inflammatory effects, and may protect against various forms of cancers. Additionally, it can be absorbed through the skin when in an ethanol base (typically perillyl alcohol).

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How to Take

Medical Disclaimer

Recommended dosage, active amounts, other details

A standard dose is 200-300mg active Rosmarinic acid (check source for extract percentage) for oral ingestion.

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Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what effects rosmarinic acid has on your body, and how strong these effects are.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-c Minor - See study
Rosmarinic acid appears to be effective in suppressing the response to pollen allergies in persons with seasonal rhinitus
grade-c Minor - See study
Nasal congestion is reduced secondary to reducing pollen allergies
grade-d Minor - See study
Topical application of rosmarinic acid may aid symptoms of atopic dermatitis

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Things to Note

Also Known As

Rosmarinus Officinalis Extract, Rosemary Extract, Perilla Frutescens extract. Perilla Extract

Do Not Confuse With

Rosemary (the plant), Rosa damascena, Roselle, Rhodiola Rosea, Perilla Oil (a major source)

Goes Well With

  • Lycopene (in regards to prevention of LDL oxidation)

  • Alcohol (for topical absorption)

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Click here to see all 36 references.