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Milk Protein

Milk protein is a blend of Casein protein and Whey protein, usually in an 80/20 blend. There really is nothing super special about it, but it can be a cheaper way of ingesting Whey and Casein protein when the difference is irrelevant for your goals since processing costs are less.

Our evidence-based analysis on milk protein features 36 unique references to scientific papers.

Research analysis led by and reviewed by the Examine team.
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  1. Lorenzen J, et al. The effect of milk proteins on appetite regulation and diet-induced thermogenesis. Eur J Clin Nutr. (2012)
  2. Poortmans JR, Dellalieux O. Do regular high protein diets have potential health risks on kidney function in athletes. Int J Sport Nutr Exerc Metab. (2000)
  3. Beasley JM, et al. Higher biomarker-calibrated protein intake is not associated with impaired renal function in postmenopausal women. J Nutr. (2011)
  4. Knight EL, et al. The impact of protein intake on renal function decline in women with normal renal function or mild renal insufficiency. Ann Intern Med. (2003)
  5. Brändle E, Sieberth HG, Hautmann RE. Effect of chronic dietary protein intake on the renal function in healthy subjects. Eur J Clin Nutr. (1996)
  6. King AJ, Levey AS. Dietary protein and renal function. J Am Soc Nephrol. (1993)
  7. Dietary protein intake and renal function.
  8. Wakefield AP, et al. A diet with 35% of energy from protein leads to kidney damage in female Sprague-Dawley rats. Br J Nutr. (2011)
  9. Aparicio VA, et al. Effects of high-whey-protein intake and resistance training on renal, bone and metabolic parameters in rats. Br J Nutr. (2011)
  10. Frank H, et al. Effect of short-term high-protein compared with normal-protein diets on renal hemodynamics and associated variables in healthy young men. Am J Clin Nutr. (2009)
  11. Wiegmann TB, et al. Controlled changes in chronic dietary protein intake do not change glomerular filtration rate. Am J Kidney Dis. (1990)
  12. Levey AS, et al. Effects of dietary protein restriction on the progression of advanced renal disease in the Modification of Diet in Renal Disease Study. Am J Kidney Dis. (1996)
  13. [No authors listed. Effects of dietary protein restriction on the progression of moderate renal disease in the Modification of Diet in Renal Disease Study. J Am Soc Nephrol. (1996)
  14. Merli M, Riggio O. Dietary and nutritional indications in hepatic encephalopathy. Metab Brain Dis. (2009)
  15. Starr SP, Raines D. Cirrhosis: diagnosis, management, and prevention. Am Fam Physician. (2011)
  16. Ong JP, et al. Correlation between ammonia levels and the severity of hepatic encephalopathy. Am J Med. (2003)
  17. Caballero VJ, et al. Alternation between dietary protein depletion and normal feeding cause liver damage in mouse. J Physiol Biochem. (2011)
  18. Oarada M, et al. Refeeding with a high-protein diet after a 48 h fast causes acute hepatocellular injury in mice. Br J Nutr. (2011)
  19. Sogawa N, et al. The changes of hepatic metallothionein synthesis and the hepatic damage induced by starvation in mice. Methods Find Exp Clin Pharmacol. (2003)
  20. Hepatocellular Injuries Observed in Patients with an Eating Disorder Prior to Nutritional Treatment.
  21. Madhavan TV, Gopalan C. The effect of dietary protein on carcinogenesis of aflatoxin. Arch Pathol. (1968)
  22. Appleton BS, Campbell TC. Effect of high and low dietary protein on the dosing and postdosing periods of aflatoxin B1-induced hepatic preneoplastic lesion development in the rat. Cancer Res. (1983)
  23. Mandel HG, Judah DJ, Neal GE. Effect of dietary protein level on aflatoxin B1 actions in the liver of weanling rats. Carcinogenesis. (1992)
  24. Blanck A, et al. Influence of different levels of dietary casein on initiation of male rat liver carcinogenesis with a single dose of aflatoxin B1. Carcinogenesis. (1992)
  25. Hornsby LB, Hester EK, Donaldson AR. Potential interaction between warfarin and high dietary protein intake. Pharmacotherapy. (2008)
  26. Bolter CP, Critz JB. Plasma enzyme activities in rats with diet-induced alterations in liver enzyme activities. Experientia. (1974)
  27. Dargent-Molina P, et al. Proteins, dietary acid load, and calcium and risk of postmenopausal fractures in the E3N French women prospective study. J Bone Miner Res. (2008)
  28. Calvez J, et al. Protein intake, calcium balance and health consequences. Eur J Clin Nutr. (2011)
  29. High-Protein Weight Loss Diets and Purported Adverse Effects: Where is the Evidence?.
  30. Thorpe M, et al. A positive association of lumbar spine bone mineral density with dietary protein is suppressed by a negative association with protein sulfur. J Nutr. (2008)
  31. Zhang X, et al. Prospective cohort study of soy food consumption and risk of bone fracture among postmenopausal women. Arch Intern Med. (2005)
  32. von Herrath D, et al. Glomerular filtration rate in response to an acute protein load. Blood Purif. (1988)
  33. Bosch JP, et al. Renal functional reserve in humans. Effect of protein intake on glomerular filtration rate. Am J Med. (1983)
  34. Skelton LA, Boron WF, Zhou Y. Acid-base transport by the renal proximal tubule. J Nephrol. (2010)
  35. Yaqoob MM. Acidosis and progression of chronic kidney disease. Curr Opin Nephrol Hypertens. (2010)
  36. Kraut JA, Madias NE. Consequences and therapy of the metabolic acidosis of chronic kidney disease. Pediatr Nephrol. (2011)