Summary of Magnolia officinalis
Primary Information, Benefits, Effects, and Important Facts
Magnolia Officinalis is a plant from the Magnolia species of plants which share a set of similar compounds. Two of them, known as Honokiol and Magnolol, are seen as the active ingredients.
Magnolia plants tend to be significantly cancer protective, and show protective effects on the liver and the brain via fighting inflammation and oxidation. They have also been linked to anti-depressant and anxiety reducing effects.
One of the compounds, Honokiol, is currently in trials for usage as an adjunct treatment for cancer therapy.
Benefits can be found with drinking Magnolia teas, known as Saiboku-to, although the tea should be consumed with meals due to the fat-solubility of the active ingredients.
Get unbiased information on what works
At Examine.com, we pride ourselves on basing all our recommendations on evidence. It’s why we don’t sell any advertising or supplements — so that you know that our analysis is unbiased.
If you’re tired of wasting time and money on supplements that don’t work, our 17 Supplement Guides will help you figure out precisely what to take — and what to skip — based on your health goals and the latest scientific evidence.
Join over 50,000 people who rely on Examine.com's unbiased and science-based analysis.
I want unbiased recommendations »
How to TakeMedical Disclaimer
Recommended dosage, active amounts, other details
The dosage of magnolia officinalis to take varies on goal. For those related to GABA (including anxiety, sedation, stress, and epilepsy) an oral dose of 0.2mg/kg in mice appears effective and suggests very lose doses (5-10 mg) are effective in humans.
For those goals related to learning or depression, higher doses may be required. This usually means 15-30mg/kg in rats, and suggests a human dose of:
160-330 mg for a 150lb person
220-440 mg for a 200lb person
270-550 mg for a 250lb person
The above doses refer to the total neolignans (usually magnolol plus honokiol), which are usually at 1-10% of a basic bark extract unless otherwise concentrated.
Get the latest information on 400+ supplements and their effects on 500+ health outcomes.
By becoming an Examine Plus member, you'll have access to all of the latest nutrition research. Quickly and easy look up evidence on over 400 supplements across over 500 different health goals, outcomes, conditions, and more.
Human Effect Matrix
The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what effects magnolia officinalis has on your body, and how strong these effects are.
|Grade||Level of Evidence [show legend]|
|Robust research conducted with repeated double-blind clinical trials|
|Multiple studies where at least two are double-blind and placebo controlled|
|Single double-blind study or multiple cohort studies|
|Uncontrolled or observational studies only|
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
|Notable||- See study|
Get access to the latest nutrition research
By becoming an Examine Plus member, you'll have access to all of the latest nutrition research on over 300 supplements across over 500 different health goals, outcomes, conditions, and more.
Things to Note
Also Known As
Saiboku-to, Magnolia Bark Extract, Honokiol, Magnolol
Do Not Confuse With
Goes Well With
Ginger (ginger enhances the antidepressive effects of magnolia officinalis)
Pinellia ternata (synergistically antidepressive)
Tired of misinformation? Get unbiased info on supplements.
At Examine.com, our incentives line up with yours — getting unbiased information. It’s why we don’t sell any advertising or supplements.
Join over 250,000 people who’ve learned about effective versus overrated supplements, supplement buying tips, and how to combine supplements for safety and efficacy.
Click here to see all 100 references.