L-Threonate
Summary of L-Threonate
Primary Information, Benefits, Effects, and Important Facts
L-Threonate is a metabolite of vitamin C that is currently being investigated for some vitamin C-like properties as well as its ability to greatly enhance mineral uptake.
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Things To Know & Note
Primary Function:
Also Known As
L-Threonic Acid
Do Not Confuse With
L-Theanine
Goes Well With
Dietary minerals as chelations
Caution Notice
Examine.com Medical DisclaimerHow to Take L-Threonate
Recommended dosage, active amounts, other details
Not enough information is known at this time to suggest an optimal dose of L-Threonate in isolation.
Mineral chelations of L-Threonate should be dosed according to the active mineral content of the chelation.
Scientific Research on L-Threonate
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References
- ^ Kwack MH, et al. Preventable effect of L-threonate, an ascorbate metabolite, on androgen-driven balding via repression of dihydrotestosterone-induced dickkopf-1 expression in human hair dermal papilla cells. BMB Rep. (2010)
- ^ Effects of ascorbic acid and ascorbic acid 2-phosphate, a long-acting vitamin C derivative, on the proliferation and differentiation of human osteoblast-like cells.
- ^ Kwack MH, et al. L-ascorbic acid 2-phosphate represses the dihydrotestosterone-induced dickkopf-1 expression in human balding dermal papilla cells. Exp Dermatol. (2010)
- ^ Enhanced Production of Mineralized Nodules and Collagenous Proteins In Vitro by Calcium Ascorbate Supplemented With Vitamin C Metabolites.
- ^ a b Wang HY, Hu P, Jiang J. Pharmacokinetics and safety of calcium L-threonate in healthy volunteers after single and multiple oral administrations. Acta Pharmacol Sin. (2011)
- ^ Fay MJ, Bush MJ, Verlangieri AJ. Effect of aldonic acids on the uptake of ascorbic acid by 3T3 mouse fibroblasts and human T lymphoma cells. Gen Pharmacol. (1994)
- ^ He JH, et al. Effects of L-threonate on bone resorption by osteoclasts in vitro. Sichuan Da Xue Xue Bao Yi Xue Ban. (2005)
- ^ Li XX, et al. A randomized controlled and multicenter clinical study of ferrous L-threonate in treatment of iron deficiency anemia. Zhonghua Nei Ke Za Zhi. (2005)
- ^ Tian W, Lin XM. Effects of iron supplementation on human serum level of transferrin receptor. Zhonghua Yu Fang Yi Xue Za Zhi. (2004)
- ^ Abumaria N, et al. Effects of elevation of brain magnesium on fear conditioning, fear extinction, and synaptic plasticity in the infralimbic prefrontal cortex and lateral amygdala. J Neurosci. (2011)
- ^ Slutsky I, et al. Enhancement of learning and memory by elevating brain magnesium. Neuron. (2010)
- ^ Gao SL, et al. FTIR studies of L-threonic acid and its metal compounds. Guang Pu Xue Yu Guang Pu Fen Xi. (2003)