DMAE

Last Updated: September 28 2022

DMAE is a choline molecule with one less methyl group, and has the ability to reduce build-up of the age pigmentation known as beta-amyloid. It is the active component of Centrophenoxine, or Lucidril, a pharmaceutical designed for cognitive health in the elderly.

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DMAE is most often used for

Summary

DMAE is a compound that is known as a mind health compound. It does this by reducing buildup of what is known as the 'age pigment', which impairs cognitive function and is implicated in the cognitive decline with age. It can also increase levels of the compound involved with memory, acetylcholine.

It can also protect neurons and other cells from harmful effects of certain types of oxidation by embedding itself in the structure of the cell and acting as an anti-oxidant, as well as sustaining metabolic processes in the body through a process known as 'methyl donation'.

DMAE is also found in various face and body creams, and can tighten and tone skin quality.

What else is DMAE known as?
Note that DMAE is also known as:
  • Dimethylaminoethanol
  • dimethylethanolamine
  • Deanol (cream)
DMAE should not be confused with:
  • DMAA (Stimulant)
  • DHEA (Hormone Precursor)
Examine Database: DMAE
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References
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4.^Tammenmaa IA, Sailas E, McGrath JJ, Soares-Weiser K, Wahlbeck KSystematic review of cholinergic drugs for neuroleptic-induced tardive dyskinesia: a meta-analysis of randomized controlled trialsProg Neuropsychopharmacol Biol Psychiatry.(2004 Nov)
6.^Soares KV, McGrath JJThe treatment of tardive dyskinesia--a systematic review and meta-analysisSchizophr Res.(1999 Aug 23)
8.^Uhoda I, Faska N, Robert C, Cauwenbergh G, Piérard GESplit face study on the cutaneous tensile effect of 2-dimethylaminoethanol (deanol) gelSkin Res Technol.(2002 Aug)
10.^Fisher MC, Zeisel SH, Mar MH, Sadler TWPerturbations in choline metabolism cause neural tube defects in mouse embryos in vitroFASEB J.(2002 Apr)
11.^Hirata F, Viveros OH, Diliberto EJ Jr, Axelrod JIdentification and properties of two methyltransferases in conversion of phosphatidylethanolamine to phosphatidylcholineProc Natl Acad Sci U S A.(1978 Apr)