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Summary of 1,3-Dimethylamylamine
Primary information, health benefits, side effects, usage, and other important details
DMAA is a neurological stimulant which causes a quick spike of energy similar to caffeine and other classical stimulants, but does so by different mechanisms in the brain.
It was first introduced as a nasal decongestant as 'Germanium Oil Extract' but more recently is used as a neurological stimulant and party pill.
Due to its structural similarity to amphetamines, it gives a false positive in drug tested competitions for amphetamines and thus should not be used by competing athletes.
It is not a highly studied compound in isolation.
It has been banned by the FDA for use in dietary supplements, but analogs are sometimes used in its place. The analog, 1,4-DMAA, now is on the FDA's Dietary Supplement Ingredient Advisory List as of April, 2019. These are ingredients that do not appear to be lawful ingredients in dietary supplements. The list is subject to change (check the provided link for current status).
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How to TakeMedical Disclaimer
Recommended dosage, active amounts, other details
A typical starting dose of 1,3-DMAA is in the 10-20mg range and eventually reaching up to 40-60mg a day, there is no actual evidence to support this dosage range but it seems to be the standard dosages range for supplemental 1,3-DMAA on the market.
1,3-DMAA is known to be banned by various sports organizations due to its amphetamine-like nature, and should not be used by tested athletes.
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Human Effect Matrix
The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what effects 1,3-dimethylamylamine has on your body, and how strong these effects are.
|Grade||Level of Evidence [show legend]|
|Robust research conducted with repeated double-blind clinical trials|
|Multiple studies where at least two are double-blind and placebo controlled|
|Single double-blind study or multiple cohort studies|
|Uncontrolled or observational studies only|
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
|Notable||- See study|
|-||- See study|
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Things to Note
Also Known As
4-methylhexan-2-amine, DMAA, Dimethylamylamine, 1, 3-DMAA, Geranamine, Methylhexaneamine, 3-Dimethylpentylamine, Forthane
DMAA may cause a false positive for amphetamines in urine testing.
The World Anti-Doping Agency has added methylhexanamine to the 2010 prohibited list, and while usage of 1,3-DMAA in the american military appears to be restricted the Australian government has classified DMAA as a Schedule 9 substance (2012) and prohibits its sales.
DMAA is highly stimulatory.
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