What are ashwagandha’s main benefits?

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Ashwagandha is best known for its anxiolytic (anti-anxiety) and stress-relieving effects.[1][2][3][4][5] It also seems to reduce cortisol levels.[6][7][3][4][8][5] In addition, a growing body of evidence supports the efficacy of ashwagandha for improving total sleep time and sleep quality in people with and without insomnia.[9]

Since the stress response has a wide range of effects on the human body, it is possible this action is where ashwagandha’s reputation for being a ‘cure all’ originated. There is increasing support for the use of ashwagandha in the context of health states that are typically affected by a chronic stress response.[10] Ashwagandha research in cardio-respiratory and musculoskeletal performance enhancements has shown promise for both athletes and non-athletes.[11][12][13][14][15][16][17] Similarly, ashwagandha may also improve immune health, women’s health, men’s health, and sexual health. Unfortunately, due to inconsistencies in the research, it has been difficult to form any direct conclusions.[18][19][20][21][22][23][24][25]

References
2.^Sara Fuladi, Seyed Ahmad Emami, Amir Hooshang Mohammadpour, Asieh Karimani, Ali Akhondpour Manteghi, Amirhossein SahebkarAssessment of Withania Somnifera Root Extract Efficacy in Patients With Generalized Anxiety Disorder: A Randomized Double-Blind Placebo-Controlled TrialCurr Clin Pharmacol.(2020 Apr 13)
4.^Kumarpillai Gopukumar, Shefali Thanawala, Venkateswarlu Somepalli, T S Sathyanaryana Rao, Vijaya Bhaskar Thamatam, Sanjaya ChauhanEfficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled StudyEvid Based Complement Alternat Med.(2021 Nov 30)
8.^A Remenapp, K Coyle, T Orange, T Lynch, D Hooper, S Hooper, K Conway, H A HausenblasEfficacy of Withania somnifera supplementation on adult's cognition and moodJ Ayurveda Integr Med.(2021 Nov 25)
9.^Kae Ling Cheah, Mohd Noor Norhayati, Lili Husniati Yaacob, Razlina Abdul RahmanEffect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysisPLoS One.(2021 Sep 24)
11.^Wankhede S, Langade D, Joshi K, Sinha SR, Bhattacharyya SExamining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trialJ Int Soc Sports Nutr.(2015 Nov 25)
12.^Ziegenfuss TN, Kedia AW, Sandrock JE, Raub BJ, Kerksick CM, Lopez HLEffects of an Aqueous Extract of Withania somnifera on Strength Training Adaptations and Recovery: The STAR TrialNutrients.(2018 Nov 20)
13.^Shenoy S, Chaskar U, Sandhu JS, Paadhi MMEffects of eight-week supplementation of Ashwagandha on cardiorespiratory endurance in elite Indian cyclistsJ Ayurveda Integr Med.(2012 Oct)
15.^Singh P, Salman KA, Shameem M, Warsi MSas Add-On Therapy for COPD Patients: A Randomized, Placebo-Controlled, Double-Blind Study.Front Pharmacol.(2022)
16.^Pérez-Gómez J, Villafaina S, Adsuar JC, Merellano-Navarro E, Collado-Mateo DEffects of Ashwagandha () on VO: A Systematic Review and Meta-Analysis.Nutrients.(2020-Apr-17)
17.^Diego A Bonilla, Yurany Moreno, Camila Gho, Jorge L Petro, Adrián Odriozola-Martínez, Richard B KreiderEffects of Ashwagandha ( Withania somnifera) on Physical Performance: Systematic Review and Bayesian Meta-AnalysisJ Funct Morphol Kinesiol.(2021 Feb 11)
18.^Bhat J, Damle A, Vaishnav PP, Albers R, Joshi M, Banerjee GIn vivo enhancement of natural killer cell activity through tea fortified with Ayurvedic herbsPhytother Res.(2010 Jan)
21.^Nasimi Doost Azgomi R, Nazemiyeh H, Sadeghi Bazargani H, Fazljou SMB, Nejatbakhsh F, Moini Jazani A, Ahmadi AsrBadr Y, Zomorrodi AComparative evaluation of the effects of Withania somnifera with pentoxifylline on the sperm parameters in idiopathic male infertility: A triple-blind randomised clinical trialAndrologia.(2018 Sep)