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Treatment of Hepatic Encephalopathy

Hepatic Encephalopathy is a liver condition associated with excessive ammonia which impairs cognitive function, and supplements that either aid liver function or independently reduce ammonia are seen as therapeutic.

Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published: Jul 5, 2013
Last Updated:

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Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect treatment of hepatic encephalopathy
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b Minor Very High See all 4 studies
Cognitive side effects of hepatic encepalopathy are alleviated with carnitine supplementation, notably fatigue and cognitive performance.