Our evidence-based analysis on inflammatory bowel disease (ibd) features 1 unique references to scientific papers.
Inflammatory bowel disease (IBD) refers to a group of chronic inflammatory conditions that affect the gastrointestinal tract. The two most common types of IBD are Crohn’s disease, which can impact any portion of the digestive system from mouth to anus, and ulcerative colitis, which is restricted to the colon and rectum. Up to 0.5% of the Western world[1] is estimated to suffer from IBD and associated medical costs may exceed $6 billion annually.
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The Human Effect Matrix looks at human studies to tell you what supplements affect Inflammatory Bowel Disease (IBD).
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| Grade | Level of Evidence [show legend] |
|---|---|
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Robust research conducted with repeated double-blind clinical trials |
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Multiple studies where at least two are double-blind and placebo controlled |
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Single double-blind study or multiple cohort studies |
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Uncontrolled or observational studies only |
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Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
|
Supplement |
Magnitude of effect
?
The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
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Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
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Notes |
|---|---|---|---|---|
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Minor
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Very High See 2 studies |
In small, open-label, uncontrolled studies, most participants with IBD experienced reductions in disease activity, but it did worsen in some cases. A single sub-study of gene expression identified some changes that could indicate elevations in regulatory T-cell activity. Our confidence in these results is very low due to the lack of control groups, small sample sizes, lack of blinding, and high risk of bias in these studies.
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