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Dry Mouth

Research analysis led by .
Reviewed by
Examine.com Team
Last Updated:
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Summary of Dry Mouth

Scientific Information on Dry Mouth

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Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect dry mouth.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-c Minor Very High See all 4 studies
Symptoms of dry mouth either caused by a disease state (Sjögren's syndrome) or as a side-effect of pharmaceuticals appears to be significantly reduced when betaine is formulated into a toothpaste at 4%. Studies currently have a potential industry influence (financing).
grade-d Notable - See study
A notable reduction in anxiety-associated dry mouth has been noted in one industry-funded study, which needs to be replicated.

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