White Kidney Bean Extract

•Last Updated: September 28 2022

White Kidney Bean extract, or Phase 2, is a dietary carbohydrate blocker similar to chlorogenic acid and is sometimes used alongside carb containing meals to reduce the absorption of carbohydrates. It does appear to work, but its potency is quite unreliable and relatively subpar.

dosage

White Kidney Bean Extract is most often used for

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Kamal Patel, MPH, MBA

Last Updated: September 28 2022

summary
Dosage information
Research breakdown
References

Summary

White Kidney Bean extract (also known by the brand Phase 2) is a carbohydrate blocker that works by inhibiting the digestion of starches.

By inhibiting their digestion, starches that are eaten are either left undigested in the gut or the amount of which is digested is reduced. These starches are either excreted and their calories not absorbed, or they are given to colonic bacteria to ferment (eat).

When given to people who are not otherwise on a diet (during their highest carb containing meal), white kidney bean extract is able to reduce body weight and body fat levels similar to simple caloric restriction. In cases of overfeeding, white kidney bean extract can alleviate the expected increase of body fat gain and blood parameters like triglycerides and blood glucose over time.

It is also possible that white kidney bean extract can protect against colon cancer in the same manner as soluble fiber.

What else is White Kidney Bean Extract known as?

Note that White Kidney Bean Extract is also known as:

Phaseolus Vulgaris
Phase 2 (Brand name)

Dosage information

Phase 2 tablets (800mg in weight comprised of 445mg phaseolus vulgaris) appear to be effective in reducing carbohydrate absorption. These tablets must be taken alongside a carbohydrate containing meal.

It is unsure if higher doses are significantly better at blocking intestinal absorption of carbohydrates or not.

Research Breakdown

1

Overview and Pharmacology

2

Phase 2

3

Colonic Activity

4

Human Studies

5

Safety Profile

6

Conclusion

References

1.^Purification and Properties of Phaseolamin, an inhibitor of alpha-amylase, from the Kidney Bean _Phaseolus vulgaris_

2.^Ishimoto M, Yamada T, Kaga AInsecticidal activity of an alpha-amylase inhibitor-like protein resembling a putative precursor of alpha-amylase inhibitor in the common bean, Phaseolus vulgaris LBiochim Biophys Acta.(1999 Jun 15)

3.^Characterization of a purified α-amylase inhibitor from white kidney beans (Phaseolus vulgaris)

4.^Liener IE, Donatucci DA, Tarcza JCStarch blockers: a potential source of trypsin inhibitors and lectinsAm J Clin Nutr.(1984 Feb)

5.^Layer P, Carlson GL, DiMagno EPPartially purified white bean amylase inhibitor reduces starch digestion in vitro and inactivates intraduodenal amylase in humansGastroenterology.(1985 Jun)

6.^Layer P, Zinsmeister AR, DiMagno EPEffects of decreasing intraluminal amylase activity on starch digestion and postprandial gastrointestinal function in humansGastroenterology.(1986 Jul)

7.^Subchronic oral toxicity of a standardized white kidney bean (Phaseolus vulgaris) extract in rats

8.^Hangen L, Bennink MRConsumption of black beans and navy beans (Phaseolus vulgaris) reduced azoxymethane-induced colon cancer in ratsNutr Cancer.(2002)

9.^Pusztai A, Grant G, Buchan WC, Bardocz S, de Carvalho AF, Ewen SWLipid accumulation in obese Zucker rats is reduced by inclusion of raw kidney bean (Phaseolus vulgaris) in the dietBr J Nutr.(1998 Feb)

10.^Layer P, Rizza RA, Zinsmeister AR, Carlson GL, DiMagno EPEffect of a purified amylase inhibitor on carbohydrate tolerance in normal subjects and patients with diabetes mellitusMayo Clin Proc.(1986 Jun)

11.^Boivin M, Flourie B, Rizza RA, Go VL, DiMagno EPGastrointestinal and metabolic effects of amylase inhibition in diabeticsGastroenterology.(1988 Feb)

12.^Udani J, Hardy M, Madsen DCBlocking carbohydrate absorption and weight loss: a clinical trial using Phase 2 brand proprietary fractionated white bean extractAltern Med Rev.(2004 Mar)

13.^A Dietary Supplement Containing Standardized Phaseolus vulgaris Extract Influences Body Composition of Overweight Men and Women

Primary Use

Secondary Use

Gut Health