It should be noted that this plant has a very low therapeutic index (difference between the effective dose and the toxic dose) and that overdosing is both easy to do and critical; supplementation is usually avoided for this reason.
How to Take
Recommended dosage, active amounts, other details
Things to Note
This plant appears to inhibit the CYP3A4 enzyme, which is known to metabolize a great deal of drugs
Get our free 5-day course on the essentials of supplementation.
At Examine, our incentives line up with yours — getting unbiased information. That's why we don’t sell any advertising or supplements.
Join over 250,000 people who have learned about effective versus overrated supplements, tips for buying supplements, and how to combine supplements for safety and efficacy.
Click here to see all 40 references.