Quick Navigation

Rauwolscine

Rauwolscine is a molecule which is very similar in structure to yohimbine, and probably similar in its effects as well; may be more potent, but limited evidence exists.

Our evidence-based analysis on rauwolscine features 4 unique references to scientific papers.

Research analysis led by .
Reviewed by
Examine.com Team
Last Updated:

Summary of Rauwolscine

Primary information, health benefits, side effects, usage, and other important details

Rauwolscine is what is known as a diastereoisomers of Yohimbine. There are 3 diastereoisomers, the other two being corynanthine and 3-epi-alpha-yohimbine. Basically, it is an alternate form of it with slightly altered properties.

It's mechanisms of action are very similar to yohimbine, as it can act as an Alpha(2)Adrenergic antagonist and thus aid in fat burning (not so much by inducing fat loss, but by alleviating pressures the body exerts to preserve fat mass; its like preventing the body from stopping the fat loss, but doesn't induce it directly). Rauwolscine shows some promise in being more effective due to higher potency on the same receptor.

It also shares the same aphrodisiac and mood-elevating effects as yohimbine, although the potency on this relative to yohimbine is not known.

Get trusted answers to health questions that matter to you

Getting an Examine.com subscription makes it easy for you to stay informed and understand the latest nutrition research.

If you’re overwhelmed by all the possibilities of supplementation and want step-by-step instructions on what supplements to take (how much, when, and in what combinations), then the Examine.com Supplement Guides are perfect for you.

Your support keeps us 100% independent, so that we never have a conflict of interest.


How to Take

Medical Disclaimer

Recommended dosage, active amounts, other details

There is insufficient information for recommending a dosage of rauwolscine, although usually the dosing of yohimbine supplementation is extrapolated onto rauwolscine.

Things to Note

Is a Form Of

Other Functions:

Primary Function:

Also Known As

Alpha-yohimbine, isoyohimbine

Do Not Confuse With

Yohimbine

Goes Well With

  • Adrenaline increasing compounds like Caffeine

Caution Notice

Rauwolscine has more potent MAO inhibitory effects than does yohimbine, and the same cautions of pairing monoamines with an MAO extend to Rauwolscine with a bit more weight.

  • Rauwolscine is highly stimulatory and may also be mood-elevating.

Get our free 5-day course on the essentials of supplementation.

At Examine.com, our incentives line up with yours — getting unbiased information. That's why we don’t sell any advertising or supplements.

Join over 250,000 people who have learned about effective versus overrated supplements, tips for buying supplements, and how to combine supplements for safety and efficacy.

Click here to see all 4 references.