Summary of Evodia rutaecarpa
Primary Information, Benefits, Effects, and Important Facts
Evodia rutaecarpa is the plant which bears the berries evodia fructae (Fruits of Evodia), which are eaten in Traditional Chinese Medicine as a warming technique. The plant is also touted to reduce pain and gastrointestinal distress, and be anti-cancer.
It has been investigated as a fat burner, but no significantly promising evidence has been shown at this moment in time. It does appear to make animals feel hotter and quite reliably so, but this is a combination of increased heat expenditure (which is a fat burning effect) and minimizing the perception of cold via TRPV1 agonism, similar to the red pepper extract capsaicin. This combination may make one feel warmer despite not increasing caloric expenditure much.
Two studies have been conducted on animals showing anti-obesity effects, but these appear to not be related to the warmth effect of Evodia fruit and they do not necessarily mean it can be used to burn fat.
Beyond that, it shows promise as an anti-cancer agent through some relatively unique mechanisms and shows limited use as a supplement; taking the active ingredients (evodiamine, rutaecarpine) out of the fruit and into a supplemental capsule drastically reduces oral bioavailability. Isolated supplements may be quite worthless outside of the colon and stomach, with fruit or an ethanolic fruit extract being needed to reach the blood in appreciable amounts
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How to TakeMedical Disclaimer
Recommended dosage, active amounts, other details
There are currently no human studies on evodia rutaecarpa berries.
Traditional usage of the berries involves making a decoction using 3-9g of the berries and then dividing said decoction into either two servings daily (morning and evening) or thrice daily (morning, noon, and evening)
Things to Note
Also Known As
Wuzhuyu, Wu Zhu Yu, Wu Zhu Yu Tang, Evodiae Fructus, Evodia Fruit, Evodia Fructae
Do Not Confuse With
Evodiamine (bioactive), Rutaecarpine (bioactive)
Goes Well With
The Rhizome of Coptis Chinesis (increases the amount of Evodia absorbed)
Known to interact with enzymes of Drug Metabolism
Isolated evodiamine and rutaecarpine have very bad absorption rates in isolation; this is not worrisome if your target is the stomach or colon (easing digestion) but if you want it in your blood you may need to consume the whole fruits of Evodia or at least an ethanolic extract of the fruits
Significant interactions of rutaecarpine and caffeine; the former effectively negates the effects of the latter
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