What is D-aspartic acid?
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D-aspartic acid and L-aspartic acid are the two naturally occurring forms of the amino acid aspartic acid.[1] Both are synthesized in the human body, they are also obtained through the diet via any dietary protein source.[1][2] While L-aspartic acid is used as a protein building block, D-aspartic acid is not.[1] Instead, D-aspartic acid has direct effects on the central nervous system and endocrine tissues.[1][3][4] This is why D-aspartic acid is also sold as a dietary supplement.
1.^D'Aniello AD-Aspartic acid: an endogenous amino acid with an important neuroendocrine roleBrain Res Rev.(2007 Feb)
2.^Ohide H, Miyoshi Y, Maruyama R, Hamase K, Konno RD-Amino acid metabolism in mammals: biosynthesis, degradation and analytical aspects of the metabolic study.J Chromatogr B Analyt Technol Biomed Life Sci.(2011-Nov-01)
3.^Usiello A, Di Fiore MM, De Rosa A, Falvo S, Errico F, Santillo A, Nuzzo T, Chieffi Baccari GNew Evidence on the Role of D-Aspartate Metabolism in Regulating Brain and Endocrine System Physiology: From Preclinical Observations to Clinical Applications.Int J Mol Sci.(2020-Nov-18)
4.^Di Fiore MM, Boni R, Santillo A, Falvo S, Gallo A, Esposito S, Baccari GCD-Aspartic Acid in Vertebrate Reproduction: Animal Models and Experimental Designs.Biomolecules.(2019-Sep-03)