Study under review: Meta-Analysis Examining the Importance of Creatine Ingestion Strategies on Lean Tissue Mass and Strength in Older Adults
This study was designed to answer three questions relating to the effects of creatine monohydrate supplementation on lean mass and strength gains in older adults performing resistance training:
What are the effects of creatine supplementation, compared to placebo?
What are the effects of different creatine doses (no more than 5 vs. more than 5 grams per day) with and without a creatine loading phase?
What are the effects of creatine supplementation only on resistance training days?
Other Articles in Issue #83 (September 2021)
Mini: Reliable associations between dietary factors and different kinds of cancer
In this Mini, we briefly describe the most reliable associations between dietary factors and cancers at various anatomical sites according to a recent umbrella review.
Deeper Dive: Another possible strike against the relationship between TMAO and heart disease
This secondary analysis of two trials found that TMAO levels go up even when consuming heart-healthy foods, raising questions about whether TMAO actually harms the heart.
Deeper Dive: An inspirational approach to lowering blood pressure
Using a device to create resistance while inhaling could help lower the blood pressure of older adults with hypertension.
Nulls: July-August 2021
A quick roundup of recent studies that found no clear evidence of an effect.
Digital self-monitoring improves adherence to habits associated with weight loss
Monitoring healthy habits using digital tools improves outcomes, according to this recent meta-analysis. However, the authors didn’t find studies lasting more than a year, leaving the longer-term impact unclear.
Meal replacements or food: which one is better for weight loss?
Meal replacements held a slight but statistically significant advantage over low-calorie diets for weight loss, but the results weren’t different compared to very-low-calorie diets. Replacing more food-based meals tended to yield better weight loss outcomes.
Deeper Dive: Evaluating the results of an exploratory trial on diet and Alzheimer’s disease biomarkers in older people
This exploratory study found evidence suggesting that a Mediterranean-style diet improves Alzheimer’s biomarkers in people with normal cognition. But its results in people with mild cognitive impairment were counterintuitive.