IGF Binding Protein Research Analysis

Summary of IGF Binding Protein

Scientific Information on IGF Binding Protein

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect igf binding protein

Grade	Level of Evidence [show legend]
	Robust research conducted with repeated double-blind clinical trials
	Multiple studies where at least two are double-blind and placebo controlled
	Single double-blind study or multiple cohort studies
	Uncontrolled or observational studies only

Outcome	Magnitude of effect ? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.	Consistency of research results ? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.	Notes
Red Clover Extract	-	Very High See all 3 studies	No influence of supplementation on circulating concentrations of any measured IGF binding protein (IGFBP-1, IGFBP-2, IGFBP-3) in any tested population.
L-Carnitine	Minor	- See study	An increase in IGF binding protein (3) has been noted following carnitine supplementation in otherwise healthy youth
Olive leaf extract	Minor	- See study	An increase in IGF binding proteins has been noted in one study (which would sequester and reduce the activity of IGF hormones); potency of this interaction unable to be determined (no reference drug)
Dehydroepiandrosterone

All comparative evidence is now gathered in our A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available here.