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IGF Binding Protein

Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published:
Last Updated:

Summary of IGF Binding Protein

Primary Information, Benefits, Effects, and Important Facts

Scientific Information on IGF Binding Protein


Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect igf binding protein
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b Red Clover Extract - Very High See all 3 studies
No influence of supplementation on circulating concentrations of any measured IGF binding protein (IGFBP-1, IGFBP-2, IGFBP-3) in any tested population.
grade-c L-Carnitine Minor - See study
An increase in IGF binding protein (3) has been noted following carnitine supplementation in otherwise healthy youth
grade-c Olive leaf extract Minor - See study
An increase in IGF binding proteins has been noted in one study (which would sequester and reduce the activity of IGF hormones); potency of this interaction unable to be determined (no reference drug)
grade-c Dehydroepiandrosterone  

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.