Supplementation of uridine seems to be in the 500-1,000mg range, with the lone human study using the higher end of this range. It is recommended to take uridine with food out of prudency, but this has not been noted to be an absolute requirement.
Uridine
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Human Effect Matrix
Unlocked for Examine membersThe Human Effect Matrix summarizes human studies to tell you what effects Uridine has on your body, how much evidence there is, and how strong these effects are.
Full details are available to Examine members.
| Grade | Level of Evidence [show legend] |
|---|---|
|
Robust research conducted with repeated double-blind clinical trials |
|
Multiple studies where at least two are double-blind and placebo controlled |
|
Single double-blind study or multiple cohort studies |
|
Uncontrolled or observational studies only |
|
Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
|
Outcome |
Magnitude of effect
?
The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
|
Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
|
Notes |
|---|---|---|---|---|
|
|
Minor
|
- See study |
Depressive symptoms in bipolar disorder have been noted to be reduced
|
|
|
|
Minor
|
- See study |
Depressive symptoms of bipolar disorder are fairly strongly reduced with uridine supplementation, but currently only open label studies are in existence
|
Studies Excluded from Consideration
Highly confounded with other nootropic compounds[1]
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Things to Note
Is a Form Of
Primary Function:
Also Known As
UDP, UMP
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