Supplementation of uridine seems to be in the 500-1,000mg range, with the lone human study using the higher end of this range. It is recommended to take uridine with food out of prudency, but this has not been noted to be an absolute requirement.
Uridine
Get the latest information on 400+ supplements and their effects on 600+ health conditions & outcomes.
By becoming an Examine Plus member, you'll have access to all of the latest nutrition research. Quickly and easily look up scientific research on over 400 supplements across over 600 different health goals, outcomes, conditions, and more.
Human Effect Matrix
Unlocked for Examine Plus membersThe Human Effect Matrix summarizes human studies to tell you what effects Uridine has on your body, how much evidence there is, and how strong these effects are.
Full details are available to Examine Plus members.
| Grade | Level of Evidence [show legend] |
|---|---|
|
Robust research conducted with repeated double-blind clinical trials |
|
Multiple studies where at least two are double-blind and placebo controlled |
|
Single double-blind study or multiple cohort studies |
|
Uncontrolled or observational studies only |
|
Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
|
Outcome |
Magnitude of effect
?
The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
|
Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
|
Notes |
|---|---|---|---|---|
|
|
Minor
|
- See study |
Depressive symptoms in bipolar disorder have been noted to be reduced
|
|
|
|
Minor
|
- See study |
Depressive symptoms of bipolar disorder are fairly strongly reduced with uridine supplementation, but currently only open label studies are in existence
|
Studies Excluded from Consideration
Highly confounded with other nootropic compounds[1]
Become an Examine Plus member to access the latest nutrition research on over 400 supplements across over 600 different health goals, outcomes, conditions, and more.
Becoming an Examine Plus member not only unlocks the Human Effect Matrix for supplements, but also all health topics on Examine.com. We neatly summarize all the latest research so you can make the best decisions for your health based on what's accurate and not out-dated information.
Things to Note
Is a Form Of
Primary Function:
Also Known As
UDP, UMP
Tired of misinformation? Get unbiased info on supplements.
At Examine.com, our incentives line up with yours — getting unbiased information. It’s why we don’t sell any advertising or supplements.
Join over 250,000 people who’ve learned about effective versus overrated supplements, supplement buying tips, and how to combine supplements for safety and efficacy.
Click here to see all 107 references.
