Phellodendron amurense
Our evidence-based analysis on phellodendron amurense features 18 unique references to scientific papers.
Summary of Phellodendron amurense
Primary Information, Benefits, Effects, and Important Facts
Phellodendron Amurense (PA), also known as CorkTree, is a chinese herb used to historically treat different forms of inflammation and bone pain.
As a plant, it contains a few potent chemicals which exert pharmacological-like properties and is of interest as a treatment for various disease states.
Evidence-based information on what works
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Things To Know & Note
Primary Function:
Also Known As
Rutaceae, Amur Cork Tree, Kihada, Nexrutine, Corktree, Huangbai
Goes Well With
Magnolia officinalis (combination known as Relora)
Caution Notice
Examine.com Medical Disclaimer-
As a whole plant, different subsets may act synergistically with each other. If attempting to replicate a dose found in one of the subcomponents (say, Berberine) it would be prudent to use the isolated component rather than the herb unless evidence suggests both are effective.
Phellodendron Amurense has both fat and water soluble components and should be taken with food to ensure everything is absorbed well
How to Take Phellodendron amurense
Recommended dosage, active amounts, other details
Although there is not enough evidence to suggest an optimal dosage, a dose of 250-500mg taken twice a day with meals is usually advocated.
Research Breakdown on Phellodendron amurense
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References
- ^ a b c d Chen ML, et al. Chemical and biological differentiation of Cortex Phellodendri Chinensis and Cortex Phellodendri Amurensis. Planta Med. (2010)
- ^ Li CY, et al. A rapid and simple determination of protoberberine alkaloids in cortex phellodendri by 1H NMR and its application for quality control of commercial traditional Chinese medicine prescriptions. J Pharm Biomed Anal. (2006)
- ^ Chan CO, et al. Analysis of berberine and total alkaloid content in cortex phellodendri by near infrared spectroscopy (NIRS) compared with high-performance liquid chromatography coupled with ultra-visible spectrometric detection. Anal Chim Acta. (2007)
- ^ a b c d Zhang Q, et al. Simultaneous determination of jatrorrhizine, palmatine, berberine, and obacunone in Phellodendri Amurensis Cortex by RP-HPLC. Zhongguo Zhong Yao Za Zhi. (2010)
- ^ a b Yang Q, et al. Determination of bioactive compounds in Cortex Phellodendri by high-performance liquid chromatography. J AOAC Int. (2010)
- ^ Miyake M, et al. Limonoids in Phellodendron amurense (Kihada). Yakugaku Zasshi. (1992)
- ^ Steinmann D, et al. Bioguided isolation of (9Z)-octadec-9-enoic acid from Phellodendron amurense Rupr. and identification of fatty acids as PTP1B inhibitors. Planta Med. (2012)
- ^ Wang H, et al. A system for screening agonists targeting beta2-adrenoceptor from Chinese medicinal herbs. J Zhejiang Univ Sci B. (2009)
- ^ Oben J, et al. Phellodendron and Citrus extracts benefit joint health in osteoarthritis patients: a pilot, double-blind, placebo-controlled study. Nutr J. (2009)
- ^ Kim JH, et al. Effect of Phellodendron amurense in protecting human osteoarthritic cartilage and chondrocytes. J Ethnopharmacol. (2011)
- ^ Lee HW, et al. Berberine promotes osteoblast differentiation by Runx2 activation with p38 MAPK. J Bone Miner Res. (2008)
- ^ a b c Lee B, et al. Phellodendron amurense and Its Major Alkaloid Compound, Berberine Ameliorates Scopolamine-Induced Neuronal Impairment and Memory Dysfunction in Rats. Korean J Physiol Pharmacol. (2012)
- ^ Lee JH, et al. Isolation and characterization of a novel glutathione S-transferase-activating peptide from the oriental medicinal plant Phellodendron amurense. Peptides. (2006)
- ^ Kim IG, et al. Screening of estrogenic and antiestrogenic activities from medicinal plants. Environ Toxicol Pharmacol. (2008)
- ^ Kalman DS, et al. Effect of a proprietary Magnolia and Phellodendron extract on stress levels in healthy women: a pilot, double-blind, placebo-controlled clinical trial. Nutr J. (2008)
- ^ Sufka KJ, et al. Anxiolytic properties of botanical extracts in the chick social separation-stress procedure. Psychopharmacology (Berl). (2001)
- ^ a b Garrison R, Chambliss WG. Effect of a proprietary Magnolia and Phellodendron extract on weight management: a pilot, double-blind, placebo-controlled clinical trial. Altern Ther Health Med. (2006)
- Oben J, et al. Phellodendron and Citrus extracts benefit cardiovascular health in osteoarthritis patients: a double-blind, placebo-controlled pilot study. Nutr J. (2008)
