Phellodendron amurense
•Last Updated: September 28 2022
Phellodendron Amurense (PA), also known as CorkTree, is a chinese herb used to historically treat different forms of inflammation and bone pain. There is not too much Western research on this herb.
Phellodendron amurense is most often used for
Last Updated: September 28 2022
Phellodendron Amurense (PA), also known as CorkTree, is a chinese herb used to historically treat different forms of inflammation and bone pain.
As a plant, it contains a few potent chemicals which exert pharmacological-like properties and is of interest as a treatment for various disease states.
Note that Phellodendron amurense is also known as:
- Rutaceae
- Amur Cork Tree
- Kihada
- Nexrutine
- Corktree
- Huangbai
Although there is not enough evidence to suggest an optimal dosage, a dose of 250-500mg taken twice a day with meals is usually advocated.
1.^Chen ML, Xian YF, Ip SP, Tsai SH, Yang JY, Che CTChemical and biological differentiation of Cortex Phellodendri Chinensis and Cortex Phellodendri AmurensisPlanta Med.(2010 Oct)
2.^Li CY, Lu HJ, Lin CH, Wu TSA rapid and simple determination of protoberberine alkaloids in cortex phellodendri by 1H NMR and its application for quality control of commercial traditional Chinese medicine prescriptionsJ Pharm Biomed Anal.(2006 Jan 23)
3.^Chan CO, Chu CC, Mok DK, Chau FTAnalysis of berberine and total alkaloid content in cortex phellodendri by near infrared spectroscopy (NIRS) compared with high-performance liquid chromatography coupled with ultra-visible spectrometric detectionAnal Chim Acta.(2007 Jun 5)
4.^Zhang Q, Cai L, Zhong G, Luo WSimultaneous determination of jatrorrhizine, palmatine, berberine, and obacunone in Phellodendri Amurensis Cortex by RP-HPLCZhongguo Zhong Yao Za Zhi.(2010 Aug)
5.^Yang Q, Zhang F, Gao SH, Sun LN, Chen WSDetermination of bioactive compounds in Cortex Phellodendri by high-performance liquid chromatographyJ AOAC Int.(2010 May-Jun)
6.^Miyake M, Inaba N, Ayano S, Ozaki Y, Maeda H, Ifuku Y, Hasegawa SLimonoids in Phellodendron amurense (Kihada)Yakugaku Zasshi.(1992 May)
7.^Steinmann D, Baumgartner RR, Heiss EH, Bartenstein S, Atanasov AG, Dirsch VM, Ganzera M, Stuppner HBioguided isolation of (9Z)-octadec-9-enoic acid from Phellodendron amurense Rupr. and identification of fatty acids as PTP1B inhibitorsPlanta Med.(2012 Feb)
8.^Wang H, Li SY, Zhao CK, Zeng XA system for screening agonists targeting beta2-adrenoceptor from Chinese medicinal herbsJ Zhejiang Univ Sci B.(2009 Apr)
9.^Oben J, Enonchong E, Kothari S, Chambliss W, Garrison R, Dolnick DPhellodendron and Citrus extracts benefit joint health in osteoarthritis patients: a pilot, double-blind, placebo-controlled studyNutr J.(2009 Aug 14)
10.^Kim JH, Huh JE, Baek YH, Lee JD, Choi DY, Park DSEffect of Phellodendron amurense in protecting human osteoarthritic cartilage and chondrocytesJ Ethnopharmacol.(2011 Mar 24)
11.^Lee HW, Suh JH, Kim HN, Kim AY, Park SY, Shin CS, Choi JY, Kim JBBerberine promotes osteoblast differentiation by Runx2 activation with p38 MAPKJ Bone Miner Res.(2008 Aug)
12.^Lee B, Sur B, Shim I, Lee H, Hahm DHPhellodendron amurense and Its Major Alkaloid Compound, Berberine Ameliorates Scopolamine-Induced Neuronal Impairment and Memory Dysfunction in RatsKorean J Physiol Pharmacol.(2012 Apr)
13.^Lee JH, Lee DH, Yu HE, Kim JH, Lee JSIsolation and characterization of a novel glutathione S-transferase-activating peptide from the oriental medicinal plant Phellodendron amurensePeptides.(2006 Sep)
14.^Kim IG, Kang SC, Kim KC, Choung ES, Zee OPScreening of estrogenic and antiestrogenic activities from medicinal plantsEnviron Toxicol Pharmacol.(2008 Jan)
15.^Kalman DS, Feldman S, Feldman R, Schwartz HI, Krieger DR, Garrison REffect of a proprietary Magnolia and Phellodendron extract on stress levels in healthy women: a pilot, double-blind, placebo-controlled clinical trialNutr J.(2008 Apr 21)
16.^Sufka KJ, Roach JT, Chambliss WG Jr, Broom SL, Feltenstein MW, Wyandt CM, Zeng LAnxiolytic properties of botanical extracts in the chick social separation-stress procedurePsychopharmacology (Berl).(2001 Jan 1)
17.^Garrison R, Chambliss WGEffect of a proprietary Magnolia and Phellodendron extract on weight management: a pilot, double-blind, placebo-controlled clinical trialAltern Ther Health Med.(2006 Jan-Feb)
Primary Use
Joints & Bones