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Milk Thistle

Milk Thistle is a herb that contains a few active ingredients collectively referred to as Silymarins. It is a nice liver therapeutic compound (to be taken after the insult to the liver) and most well known for that, similar in mechanism to TUDCA.

Our evidence-based analysis on milk thistle features 33 unique references to scientific papers.

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Human Effect Matrix

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The Human Effect Matrix summarizes human studies to tell you what effects Milk Thistle has on your body, how much evidence there is, and how strong these effects are.

Full details are available to Examine members.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-d Notable - See study
There is a significant decrease in total lesion counts in those who supplement Silymarin daily for at least eight weeks.

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Things to Note

Also Known As

Marian thistle, Mary thistle, St Mary’s thistle, Our Lady’s thistle, Holy thistle, Sow thistle, Blessed Virgin thistle, Christ’s crown, Venue thistle, Heal thistle, Variegated Thistle, Wild Artichoke, Carduus Marianus, Silybum marianum

Do Not Confuse With

Artichoke Extract (despite Milk Thistle being known as 'Wild Artichoke'), Sphaeranthus Indicus (East Indian Thistle)

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Click here to see all 33 references.